RT Journal Article
SR Electronic
T1 Outcomes and complications of patients with cerebral venous thrombosis: a retrospective study
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 32
OP 36
DO 10.17712/nsj.2024.1.20230050
VO 29
IS 1
A1 Almegren, Mosaad O.
A1 Alharbi, Saleh H.
A1 Alshuaibi, Turki A.
A1 Almansour, Mohammed M.
A1 Alharbi, Khalid A.
A1 Al Rawahi, Bader
A1 Al Balushi, Abdulmajeed K.
A1 Alraizah, Abdulrahman A.
A1 Alqahtani, Farjah H.
YR 2024
UL http://nsj.org.sa/content/29/1/32.abstract
AB Objectives: To assess outcomes and complications of patients with cerebral venous thrombosis (CVT).Methods: This multicenter retrospective study was conducted at 2 health care centers in Saudi Arabia and Oman. Adult patients diagnosed with CVT in radiological imaging between 2006 and 2020 were included. Data were collected from medical records and analyzed using the software IBM® SPSS version 22. Neurological disability occurring after CVT was graded according to the modified Rankin scale (mRS).Results: The study included 103 patients, of which the majority (68%) were female. The mean age was 39.12±12.96 years. Two-thirds of patients received low-molecular-weight heparin (LMWH) in acute treatment, while 76% of discharged patients used warfarin. The majority of patients had no or mild neurological disability during follow-up, and 6 patients had an mRS score ≥3, implying significant neurological disability. There were 55 patients (52.3%) who had complications from CVT, including seizures in 17 (16.5%) patients and one mortality. Follow-up imaging of 55 patients showed complete thrombus resolution in 20 patients (36%).Conclusion: Anticoagulation is the mainstay treatment for CVT patients. Approximately half of patients experience complications. Prospective studies are needed to assess the long-term neurological outcomes in such patients.