RT Journal Article
SR Electronic
T1 Metabolic and genetic disorders mimicking cerebral palsy
JF Neurosciences Journal
JO Neurosciences (Riyadh)
FD Prince Sultan Military Medical City
SP 155
OP 163
DO 10.17712/nsj.2019.3.20190045
VO 24
IS 3
A1 Wejdan S. Hakami
A1 Khaled J. Hundallah
A1 Brahim M. Tabarki
YR 2019
UL http://nsj.org.sa/content/24/3/155.abstract
AB Cerebral palsy is a syndrome that encompasses a large group of childhood movement and posture disorders that result from a lesion occurring in the developing brain. The clinical presentation of many metabolic and genetic conditions, particularly in highly consanguineous populations, can mimic cerebral palsy particularly at early age. The aim of this review article is to identify the clinical features that should alert the physician to the possibility of disorders that resemble cerebral palsy, the clinical and neuroimaging red flags, and highlight some metabolic and genetic conditions which may present with spasticity, ataxia and dyskinesia. In the case of metabolic or genetic disorder, making a precise diagnosis is particularly important for the possibility of treatment, accurate prognosis and genetic counseling.