PT - JOURNAL ARTICLE AU - Chen, Hai AU - Lin, Fangju AU - Liu, Shimeng AU - Da, Yuwei AU - Guo, Dongmei TI - Neurological manifestations, laboratory and neuroimaging features in HIV-infected patients AID - 10.17712/nsj.2017.4.20160606 DP - 2017 Oct 01 TA - Neurosciences Journal PG - 311--315 VI - 22 IP - 4 4099 - http://nsj.org.sa/content/22/4/311.short 4100 - http://nsj.org.sa/content/22/4/311.full SO - Neurosciences (Riyadh)2017 Oct 01; 22 AB - Objectives: To present detailed information regarding these aspects in Human Immunodeficiency Virus (HIV)-infected patients making an effort to improve the recognition of neurological complications of HIV infection.Methods: This retrospective study analyzed the clinical manifestations, laboratory and neuroimaging results of HIV-infected patients with neurological complications at Xuanwu hospital, Beijing, China from January 2011 to December 2014, one of top-rated hospitals in Beijing, China.Results: A diverse range of clinical diagnoses was identified, including encephalopathy, meningoencephalitis, peripheral neuropathy, multiple sclerosis, cerebral infarction and lymphoma associated with HIV infection. The mostly observed neurological disorders were motor/sensory deficits in the limbs (75%), cognitive impairments (42%) and fever (33%). Non-specific results of laboratory tests, including elevated erythrocyte sedimentation rate (ESR), cerebrospinal fluid (CSF) protein concentration and IgG, were found. Brain Magnetic Resonance Imaging (MRI) abnormalities displayed a variety of patterns and distributions due to diverse clinical profiles.Conclusion: The clinical scenarios of HIV-infected patients are remarkably diverse and complex. Etiological tests would be cardinal to make more definitive diagnosis for HIV-infected patients. Prospective studies with follow-up were needed to bring more accurate information.