The characteristics, clinical presentation, imaging features, pathological confirmation, treatment methods, and outcomes of all clinically reported cases.
| Authors | Age/Gender | Comorbidities | Clinical course | Radiological features of CC | Pathology confirmation | Treatment | Outcome/Follow-up period | |
|---|---|---|---|---|---|---|---|---|
| (2) | 35/F | A known case of a colloid cyst, as well as progressive headaches and memory disturbances, followed by progressive deterioration and 2 seizure episodes. | + | + | Emergency ventriculostomy followed by endoscopic subtotal excision of the cyst. | Poor; after few months post-op, was still fully dependent on others. | ||
| (3) | 9/F | Headache, nausea, and sudden deterioration in mental status. | + | + | Emergency ventriculostomy, followed by craniotomy and cyst excision. | Tolerated the procedure well and was discharged on postoperative day 3 without any neurological complications. | ||
| (9) | 48/M | Headaches and a memory deficit for 2 weeks, followed by sudden deterioration. | + | NA | Stereotactic aspiration with limited evacuation. Followed by ventricular drainage due to herniation. Renewed stereotactic aspiration with endoscopic guidance and subtotal excision of the cyst. | Residual cyst with a slow increase in cyst size, radiologically. | ||
| (10) | 29/F | Mental status deterioration, Glasgow Coma Scale 4 with respiratory insufficiency. | + | + | Emergency ventricular drainage followed by endoscopic removal. | The radiological results were excellent, but there were poor clinical outcomes (vegetative state). | ||
| (11) | 47/M | Hypertension | Acute right-sided hemiparesis and speech impediment, followed by rapid deterioration of consciousness. | + | + | Emergency EVD followed by elective total resection of the lesion via a transcallosal route. | Right-sided hemiparesis (3/5) with impaired propioception and a mixed-type sensitive and motor dysphasia (1 year post-op). A neuropsychological assessment revealed bradipsychia and anosognosia, as well as attention, concentration, and memory deficits. | |
| (12) | 48/M | A 4-day progressive headache followed by the sudden onset of 24-hour anterograde amnesia. (Normal neurological examination without papilloedema.) | + | + | Emergency neuro-endoscopic total excision of the cyst. | The patient’s amnesia completely resolved within 24 hours post op, and he was discharged home 2 days later. Returned to full-time employment (2 months post-operatively). | ||
| (13) | 28/ M | Known case of a colloid cyst with unilateral hydrocephalus and a right ventriculo-peritoneal shunt for 8 years. Presented with severe headache and multiple episodes of vomiting for 1 day. | + | + | Right frontal craniotomy, with total excision of the cyst (an anterior interhemispheric, transcallosal–ransventricular approach). EVD for 3 days. | At 1-year follow-up, he has no neurological deficits and the headache has resolved. | ||
| (14) | 77/M | Type II diabetes mellitus. On warfarin for atrial fibrillation; INR: 1.2 | Unsteady gait, incontinence, and gradually worsening confusion over 3 weeks. The GCS was 14, with mild right-sided weakness; power 4/5. The cranial nerves were intact. | + | + | Right frontal craniotomy with total excision of the cyst. (transcortical approach). Ventriculoperitoneal shunt for delayed hydrocephalus. | Satisfactory with rehabilitation. | |
| (15) | 20/F | Progressive headache, three episodes of generalized tonic clonic seizures, gait disturbances, impaired short-term memory, bilateral papilloedema, extensor plantar reflex and (+) Romberg’s sign. | + | + | Right frontoparietal craniotomy with total excision of the cyst (interhemispheric transcallosal approach). | Seizure-free and improved memory function in 3 weeks. | ||
| (16) | 47/ F | Headache, N/V, papilledema, GCS of 13. | + | + | Ventriculostomy followed by craniotomy and total excision of the cyst. | Uneventful recovery. | ||
| (17) | 35/M | Progressive increasing headaches over months; nausea, transient loss of consciousness, and incontinence. | + | + | Total removal of the cyst (transcallosal approach). | No neurological complications. | ||
| (18) | 43/M | Known case of colloid cyst of the third ventricle without evidence of ventriculomegaly for 6 years; presented with sudden onset of headache. Intact level of consciousness with no neurological deficits. | + | + | Elective endoscopic partial removal of the cyst. | Resolved headache postoperatively without any neurological deficits. Follow-up imaging demonstrated a gradual reduction in the residual cyst size and normalization of the size of the lateral ventricle. | ||
| (19) | 45/M | Headache and malaise initially, then rapid deterioration of consciousness; GCS of 3. | + | + | EVD initially on each side. Intensive care unit admission where brain death was certified. This was followed, however, by craniotomy with excision of the cyst (transcortical frontal approach). | Brain death. | ||
| Case 1 | 47/M | Type II diabetes mellitus, long-term smoker. | Progressive morning headaches for 10 days associated with nausea and vomiting. Bilateral papilledema. | + | + | Frontal craniotomy and interhemispheric transcallosal transventricular approach for cyst excision. Left frontal EVD. | Resolved headache. | |
| Case 2 | 51/M | Progressive memory disturbance and unsteady gait for 8 months. Bilateral papilledema. | + | + | Left frontal craniotomy and transcallosal resection of the colloid cyst. | Aphasia postoperatively, which improved with speech therapy. Unsteady gait demonstrated slight improvements. | ||
M - male, F - female, EVD - external ventricular drain, ND - no data.