- Strength and level of evidence for the recommendations for the abortive treatment.
| Recommendations | Strength of recommendation | Certainty of evidence | Percentage of panel agreement |
|---|---|---|---|
| Abortive Treatment | |||
| 1. For the treatment of mild-to-moderate migraine pain, we recommend using paracetamol (acetaminophen) over no treatment. | Strong | Moderate | 100% |
| 2. For the treatment of mild-to-moderate migraine pain, we recommend using ibuprofen over no treatment. | Strong | Moderate | 100% |
| 3. For the treatment of moderate-to-severe migraine pain, we suggest using celecoxib over no treatment. | Strong | Moderate | 91% |
| 4. For the treatment of moderate-to-severe migraine pain, we suggest using sumatriptan over no treatment. | Conditional | Low | 82% |
| 5. For the treatment of acute migraine in patients receiving other triptans or ergotamine within 24 hours, we recommend against using rizatriptan. | Strong | Very low | 91% |
| 6. For the treatment of acute migraine attacks in patients with nausea or vomiting, we suggest using metoclopramide over no treatment. | Conditional | Low | 91% |
| 7. For the treatment of acute migraine in patients receiving other triptans or ergotamine within 24 hours, we recommend against using eletriptan. | Strong | Very low | 91% |
| 8. For the treatment of moderate-to-severe migraine, we suggest using rimegepant over no treatment. | Conditional | High | 100% |
| 9. For the treatment of moderate to severe migraine, we suggest using ubrogepant over no treatment. | Conditional | Low | 82% |
| 10. For the treatment of moderate to severe migraine pain, we recommend using eletriptan over no treatment. | Strong | High | 100% |
| 11. For the treatment of moderate to severe migraine attacks, we suggest against using lasmiditan. | Conditional | Moderate | 82% |
| 12. For the treatment of intractable and status migrainosus, we suggest using valproate over ibuprofen. | Conditional | Low | 100% |
| 13. For the treatment of acute migraine in the emergency department, we suggest using either valproate or dexamethasone. | Conditional | Very low | 100% |