- Factors for optimal drug selection.
| Evidence of efficacy |
|---|
| Medical professional experience |
| Tolerability |
| Patient preference |
| Headache subtype (episodic or chronic) |
| Comorbid and coexistent illnesses |
| Concomitant medications |
| Physiological factors (e.g., heart rate, blood pressure) |
| Pregnancy or the potential for pregnancy among women |
| Ease of use |
| Response to previous treatments |