Human leukocyte antigen (HLA) class II DRB genotypes in Iraqi Arab patients with Guillain-Barré Syndrome in comparison with a healthy control group.
| HLA-alleles | Guillain-Barré syndrome patients group (n=30) | Healthy control group (n=42) | Odds ratio (95% confidence interval) | P-value |
|---|---|---|---|---|
| n (%) | ||||
| DRB1* | ||||
| 03:01 | 14 (46.7) | 4 (9.5) | 8.312 (2.36-29.17) | 0.0009 |
| 03:17 | 0 | 5 (11.9) | NA | NA |
| 03:42 | 2 (6.7) | 0 | NA | NA |
| 03:76 | 2 (6.7) | 0 | NA | NA |
| 04:01 | 4 (13.3) | 0 | NA | NA |
| 07:01 | 12 (40.0) | 2 (4.8) | 13.33 (2.7-65.84) | 0.0015 |
| 08:01 | 0 | 2 (9.1) | NA | NA |
| 11:01 | 4 (13.3) | 2 (4.8) | - | 0.213 |
| 11:02 | 2 (2.6) | 2 (4.8) | - | 0.729 |
| 11:03 | 0 | 7 (16.7) | NA | NA |
| 11:119 | 2 (6.7) | 0 | NA | NA |
| 11:13 | 2 (6.7) | 0 | NA | NA |
| 11:67 | 0 | 8 (19.0) | NA | NA |
| 12:01 | 4 (13.3) | 0 | NA | NA |
| 12:09 | 0 | 2 (4.8) | NA | NA |
| 13:01 | 6 (20.0) | 2 (4.8) | - | 0.44 |
| 13:05 | 0 | 3 (7.1) | NA | NA |
| 13:116 | 0 | 5 (11.9) | NA | NA |
| 13:119 | 0 | 8 (19.0) | NA | NA |
| 13:18 | 0 | 4 (9.5) | NA | NA |
| 14:01 | 0 | 2 (4.8) | NA | NA |
| 14:02 | 0 | 3 (7.1) | NA | NA |
| 14:16 | 0 | 3 (7.1) | NA | NA |
| 14:57 | 0 | 4 (9.5) | NA | NA |
| 15:01 | 6 (20.0) | 0 | NA | NA |
| DRB3* | ||||
| 01:01 | 24 (80.0) | 40 (95.0) | - | 0.0602 |
| DRB4* | ||||
| 01:01 | 18 (60.0) | 2 (4.7) | 30.000 (6.07-148.14) | 0.0001 |
| DRB5* | ||||
| 01:01 | 4 (13.3) | 0 | NA | NA |