The SPMS subjects had higher EDSS and smaller CCV and CCI.
| Variables | RRMS (N=22) Median (range) | SPMS (N=8) Median (range) | *p-value |
|---|---|---|---|
| Age of onset | 29.5 (17-52) | 23.5 (15-28) | 0.06 |
| EDSS | 3 (0-7) | 6 (3.5-8) | 0.003 |
| CCV | 2459.35 (1446.3-2306.1) | 1729 (617.8-1924) | 0.0004 |
| CCI | 0.33 (0.19-0.44) | 0.24 (0.21-0.28) | 0.008 |
↵* Mann Whitney U test
EDSS - Extended Disability Status Scale
CCV - Corpus Callosum Volume
CCI - Corpus Callosum Index
RRMS - Relapsing Remitting Multiple Sclerosis
SPMS - Secondary Progressive Multiple Sclerosis