Table 1

Characteristics of studies included in the systematic review.

s/no	Author, (year)	Countries	Study period	Type of MG	Total number of Patients	Recurrence	Mean/Median Follow-up period (years)
1	Palmisani, (1994)	Italy	1971-1991	Thymoma	111	20	>1
2	Mano, (1993)	Japan	N/A	Both	105	50	9.8
3	Ohmi, (1991)	Japan	1977 – 1989	Both	166	3	>1
4	Abo Elnasr, (2016)	Egypt	2013-2015	Non-thymoma	38	9	0.5
5	Budde, (2001)	USA	1974-1999	Both	92	23	4.3
6	Meyer, (2009)	USA	1992-2006	Both	81	3	6.0±4.0
7	Masaoka, (1996)	Japan	1973 – 1993	Both	321	47	1
8	Bachmann, (2009)	Germany	1980 – 2005	Non thymoma	84	23	9.8
9	Maggi, (2008)	Italy	1986 - 2006	Thymoma	197	62	7.69±6.0
10	Venuta, (1999)	Italy	1970 – 1997	Both	204	51	9.92
11	Kaufman, (2016)	USA	1941-2013	Both	1002	647	6
12	Poomthong, (2012)	Thailand	2010	Non thymoma	51	25	1
13	Glinjongol, (2004)	Thailand	1990-2004	Both	30	6	3.4
14	Ozdemir, (2003)	Turkey	1990-2000	Both	61	11	3.83
15	Takanami, (2009)	Japan	1991-2005	Both	54	18	6.0 ± 3.9
16	Soleimani, (2004)	Iran	1985 - 2002	Both	110	20	6.4 ± 4.3
17	¹Nazarbaghi, (2015)	Iran	1999 - 2013	Both	25	0.5	7.3±4.2
18	Kumar, (2011)	India	1991 - 2007	Both	73	15	5.65
19	De Roxas, (2016)	Philippines	2009 – 2014	Both	69	27	1 year
20	Frist, (1994)	USA	1971 – 1992	Both	46	6	1
21	Gao, (2016)	China	2010 – 2014	Both	130	28	1.5
22	Hsu, (2006)	Taiwan	1986 - 2001	Both	154	62	1
23	Kim, (2018 )	South Korea	1994 - 2016	Both	179	14	1
24	Muhammed, (2016)	Malaysia	2002 – 2012	Both	16	2	1 year
25	Mulder, (1989)	USA	1983 – 1987	Both	84	17	3.6
26	El-Medany, (2003)	Saudi Arabia	1986 – 2001	Both	100	18	7.6
27	Romi, (2003)	Norway	1973 - 2002	Both	48	33	8.7
28	Téllez-Zenteno, (2001)	Mexico	1987 – 1997	Both	132	41	3
29	Tsinzerling, (2007)	Sweden	1956 – 2006	Both	537	88	1.5
30	Werneck, (2000)	Brazil	1973 – 1995	Both	28	2	6.3
31	Yang, (2017)	China	2003 – 2013	Non-thymoma	123	19	4.42
32	Yu, (2015)	China	1984 – 2001	Both	297	56	8.6
33	Dube, (2017)	India	1993 – 2014	Thymoma	8	1	4.6
34	Zheng, (2017)	China	2013 – 2016	Both	73	16	2.2
35	Lin, (2010)	Taiwan	1995 – 2004	Non thymoma	60	9	3.7
36	Bachmann, (2008)	Germany	1980 - 2005	Both	98	17	8
37	Nieto, (1999)	Spain	1977 – 1994	Both	61	2	1
38	Jaretzki, (1988)	USA	1997 – 1985	Both	95	7	0.5
39	Calhoun, (1999)	USA	1989 – 1998	nonthymoma	78	12	5.0
40	Shrager, (2002)	USA	1992 – 1999	Both	78	8	4.6
41	Detterbeck, (1996)	USA	1977 – 1993	Both	100	22	5.4
42	de Perrot, (2001)	Switzerland	1979 – 1999	Both	35	26	8
43	Tansel, (2003)	Turkey	1980 – 2001	nonthymoma	204	20	7.2± 1.2
44	Siwachat, (2018)	Thailand`	2006 – 2013	Both	98	11	3.48
45	Seyfari, (2018)	Iran	2011 – 2015	Both	47	7	1
46	Waitande, (2007)	India	1994 – 2003	Both	57	17	2.4
47	Kattach, (2006)	United Kingdom	1987 - 1998	Both	85	3	4.5
48	Huang, (2005)	Taiwan	1986 - 2000	Both	154	18	8.2
49	Hase, (2006)	Japan	1987 – 2001	Both	17	4	0.5
50	Remes-Troche, (2002)	Mexico	1989 – 2000	Both	152	49	2
51	Pompeo, (2009)	Italy	1995 – 20003	Non thymoma	32	5	9.92
52	Liu, (2016)	China	2000 - 2010	Both	31	10	6.9
53	Yu, (2014)	China	1997 – 2012	Both	188	36	5.6
54	Busch, (1996)	Germany	1976 - 1993	Both	86	25	8.0
55	Bril, (1998)	Canada	1977 – 1986	Nonthymoma	52	5	8.4
56	Klein, (1999)	Germany	1984 – 1992	Both	51	7	3.9
57	Mineo, (2000)	Italy / Belgium	1993 – 1997	Both	31	1	3.3
58	Zielinski, (2004)	Poland	2000 – 2003	Nonthymoma	48	8	1
59	Yim, (2002)	Hong Kong	1985– 2000	Both	36	8	3.4
60	Manlulu, (2005)	China	1992 – 2004	Nonthymoma	36	3	5.8
61	Savcenko, (2002)	USA	1992 – 2002	Both	36	6	4.4
62	Uchiyama, (2001)	Japan	1998 – 2000	Both	23	2	1
63	Wright, (2002)	Australia	1997 – 2001	Nonthymoma	24	2	0.5
64	Nussbaum, (2002)	USA	1979 – 1991	Both	48	3	4.3
65	Cooper, (1988)	Canada	1977 – 1986	Both	65	3	3.5
66	Olanow, (1987)	Canada	1979 – 1986	Both	55	5	3.3
67	DeFilippi, (1994)	USA	1977 - 1991	Nonthymoma	21	4	4.3
68	Mack, (1996)	USA	1992 – 1995	Both	33	4	1.9
69	Ambrogi, (2012)	Italy	1980 – 2005	Nonthymoma	96	24	13.3
70	Mineo, (2013)	Italy	1980 - 2007	Nonthymoma	47	9	8.3

¹= no recurrence during follow-up, 0.5 was assigned to allow for meta-analysis; N/A = not available