- Summary of studies on IA of CNS in immunocompetent patients in Saudi Arabia including the current study.
Study period | n | Age: mean(range) | Male/female | Aspergillus spp. | Treatment anti-fungal | Clinical outcome | Follow up (months) |
---|---|---|---|---|---|---|---|
Mohan et al7 (1987–92) | 4 | 42.2 (30–60) | 2/2 | A. flavus (4) | Surgery/Amphotericin B | 3 no recurrence | 12-24 months |
1 death | |||||||
Ur-Rahman8 et al. (1983–94) | 9 | 47.3 (26–66) | 1/8 | A. flavus (6) | Surgery/Amphotericin B plus flucytosine then itraconazole | 1 cured | 1-36 months |
6 residual or lost f/up | |||||||
A. fumigatus (3) | |||||||
2 death | |||||||
Baeesa et al9 (2000–12) | 12 | 32 (17–50) | 4/8 | not defined | Surgery/Amphotericin B plus itraconazole or variconazole | 8 cured | 12–50 months |
2 residual or recurrence | |||||||
2 deaths | |||||||
Taha et al (2012–18) | 3 | 33 (30–36) | 3/0 | not defined | Surgery/Amphotericin B plus variconazole | 1 cured | 1-18 months |
2 deaths |