Table 2

- Clinical characteristics.

Patient/Clinical diagnosisEEGBrain imagingDevelopment
Stroke and epilepsyGeneralized epileptic dischargesinfarction, watershed, bilateral parietal occipitalGDD
Infantile spasms, Down syndrome, congenital heart diseaseHypsarrhythmiaNormalGDD
Dravet syndromeGeneralized epileptic dischargesAtrophy and encephalomalacia post meningitisGDD
Birth asphyxia. Lennox-Gastaut syndromeGeneralized epileptic dischargesSevere atrophy and hypoxia related changesGDD
Birth asphyxiaGeneralized epileptic dischargesSevere atrophy and hypoxia related changesGDD
Neurometabolic disease, Dandy–Walker malformation, global developmental delayGeneralized epileptic discharges & encephalopathyDandy–Walker malformation and brain atrophyGDD
Focal epilepsyTemporal dischargesNormalNormal
Propionic acidemia, neurodegenerative brain disorderEncephalopathyAtrophyGDD
Neurodegenerative brain disorderEncephalopathyAtrophy, white matter abnormalitiesGDD
Hydrocephalus, Arnold-Chiari malformation, MMC (Myelomeningocele)EncephalopathyHydrocephalus, Arnold-Chiari malformationGDD
Chromosomal 18q- syndrom, multiple congenital anomaliesGeneralized epileptic discharges & encephalopathyPeriventricular white matter volume loss, corpus callosum hypoplasiaGDD
Infantile spasms, hyperglycinemiaHypsarrhythmiabrain atrophy, hypoplastic corpus callosumGDD
Dysmorphic features, caudal regression syndromeGeneralized epileptic dischargesWhite matter volume lossGDD
Neurodegenerative brain disease, progression of milestones, hypopituitarismFocal dischargesHydrocephalusGDD
Aicardi syndromeHypsarrhythmiahypoplastic corpus callosumGDD
NCLGeneralized epileptic dischargesBrain atrophyGDD
Down syndrome, birth asphyxiaGeneralized epileptic discharges & encephalopathyHypoxia changesGDD
Preterm, birth asphyxiaGeneralized epileptic discharges & encephalopathyBrain atrophyGDD
Birth asphyxiaEncephalopathyBrain atrophyGDD
Neurometabolic disease, glutamine synthase deficiencyEncephalopathyColpocephaly with dilation of lateral ventriclesGDD
Idiopathic epilepsyGeneralized epileptic dischargesNormalGDD
  • *GDD - Global developmental delay, *NCL - neuronal ceroid lipofuscinosis, MMC - Myelomeningocele