Table 3

- Comparison of NOS3 genotype and allele frequency distributions of rapid cycling BD patients with non-rapid cycling BD patients and the control groups.

Genotypes	Rapid cycling yes	Rapid cycling no	OR	95% CI	P-value
NOS3	n=20 (%)	n=75 (%)
b/b	9 (45)	57 (76)	0.258^*	0.092-0.722^*	.007^*
b/a	9 (45)	16 (21.3)	3.017^*	1.067-8.534^*	.033^*
a/a	2 (10)	2 (2.7)	0.247&	0.032-1.871&	.194&
Allele
b	27 (67.5)	130 (86.7)
a	13 (32.5)	20 (13.3)	3.130^*	1.389-7.049^*	.004^*
NOS3		Healthy control
b/b	9 (45)	77 (81.1)	0.191^*	0.069-0.530^*	.001^*
b/a	9 (45)	17 (17.9)	3.754&	1.347-10.466&	.016&
a/a	2 (10)	1 (1.1)	10.444&	0.899-121.379&	.078&
Allele
b	27 (67.5)	171(90)
a	13 (32.5)	19 (10)	0.231^*	0.102-0.521^*	.000^*

OR - odds ratio, CI - confidence interval,

↵* Pearson chi-square &Fisher’s Exact Test