Genotypes | Rapid cycling yes | Rapid cycling no | OR | 95% CI | P-value |
---|---|---|---|---|---|

NOS3 | n=20 (%) | n=75 (%) | |||

b/b | 9 (45) | 57 (76) | 0.258^{*} | 0.092-0.722^{*} | .007^{*} |

b/a | 9 (45) | 16 (21.3) | 3.017^{*} | 1.067-8.534^{*} | .033^{*} |

a/a | 2 (10) | 2 (2.7) | 0.247& | 0.032-1.871& | .194& |

Allele | |||||

b | 27 (67.5) | 130 (86.7) | |||

a | 13 (32.5) | 20 (13.3) | 3.130^{*} | 1.389-7.049^{*} | .004^{*} |

NOS3 | Healthy control | ||||

b/b | 9 (45) | 77 (81.1) | 0.191^{*} | 0.069-0.530^{*} | .001^{*} |

b/a | 9 (45) | 17 (17.9) | 3.754& | 1.347-10.466& | .016& |

a/a | 2 (10) | 1 (1.1) | 10.444& | 0.899-121.379& | .078& |

Allele | |||||

b | 27 (67.5) | 171(90) | |||

a | 13 (32.5) | 19 (10) | 0.231^{*} | 0.102-0.521^{*} | .000^{*} |

OR - odds ratio, CI - confidence interval,

↵* Pearson chi-square &Fisher’s Exact Test