Table 5

- Comparison of scale scores and clinical parameters regarding the NOS3 intron 4 genotype distributions of BD patients.

Scale Scores and Clinical Parameters(b/b) (n= 66)(b/a, a/a) (n=29)*P-value
Median (min-max)Mean±SDMedian (min-max)Mean±SD
HAM-D score9(0-31)11.39 ±6.969(0-34)11.31±8.67.771
YMRS score6(0-37)7.48±8.081(0-35)9.03±10.10.575
CGI-S score5(2-7)4.96±0.915(3-6)5.10±0.90.297
CGI-I score2(1-4)1.96±0.822(1-4)2.37±0.94.037
Dep. episode0(0-12)1.63±2.650(0-9)1.37±2.19.604
Manic episode2.5(0-21)3.69±3.542(1-25)6.27±6.98.388
Total episode4(1-23)5.31±4.634(1-27)7.65±7.03.311
Age of onset23.5(10-52)25.89±9.3424(13-44)24.51±7.06.647
Duration of disease13.5(0.5-40)14.25±9.0118(1-40)19.75±13.22.081
Number of hospt.2(0-18)2.75±3.102(0-21)5.79±6.39.040

SD - standard deviation, min - minimum, max - maximum, CGI-S - clinical global impression scale-severity, CGI-I - clinical global impression scale-improvement, HAM-D - Hamilton depression rating scale, YMRS - Young mania rating scale, dep - depressive, hospt - hospitalization

  • * Mann Whitney U test,