- Demographic and clinical findings of population.
| Characteristics | Patients (n=152) | Controls (n=98) | P-value |
|---|---|---|---|
| Mean±SD n (%) | |||
| Age, y | 39.06±10,91 | 41.18±13.75 | 0.199 |
| Gender | |||
| Female (%) | 108 (71.1) | 68 (69.4) | 0.778 |
| Male (%) | 44 (28.9) | 30 (30.6) | |
| Education levels | |||
| Low (<8 years) Middle (9-12 years) High (>12 years) | 74 (48.7) 31 (20.4) 47 (30.9) | 48 (48.9) 19(19.3) 31(31.6) | 0.221 |
| Mean relaps number | 3.68±2.67 | ||
| Mean EDSS score | 2.13±1.69 | ||
| Mean disease duration, years | 10.42±6.47 | ||
| Clinical form | |||
| CIS | 10 (6.6) | ||
| RRMS | 119 (78.63) | ||
| SPMS | 23 (15.1) | ||
| Symptom onset | |||
| Sensorial | 47(30.9) | ||
| Motor | 41(27) | ||
| Optic neuritis | 35(23) | ||
| Brainstem | 22(14.5) | ||
| Others | 7 (4.6) | ||
| Treatment | |||
| Interferonβ-1a | 61 (40.1) | ||
| Glatiramer Acetate | 43(28.2) | ||
| Teriflunomide Dymetyl fumarate Fingolimode Ocrelizumab None | 8(5.2) 5(3.2) 8(5.2) 20(13.1) 7(4.6) | ||
| Cognitive symptoms | |||
| Yes No | 96(63.2) 56(36.8) | ||
EDSS - Expanded Disability Status Scale, CIS - Clinically Isolated Syndrome, RRMS - Relapsing Remitting Multiple Sclerosis, SPMS - Secondary Progressive Multiple Sclerosis