Characteristics | n (%) |
---|---|
Age in years Mean±SD | 34.2±16.6 |
Disease duration in months Mean±SD | 25.7±8.9 |
Gender | |
Male | 40 (27.2) |
Female | 107 (72.8) |
Clinical presentation | |
Ocular | 84 (57.1) |
Bulbar | 40 (27.2) |
Generalized | 23 (15.6) |
Anti AChR antibody | |
Positive | 130 (88.4) |
Anti-MuSK antibody | |
Positive | 8 (5.4) |
Double seronegative | 11 (7.5) |
RNS | |
Decremental response | 65 (44.2) |
Normal | 24 (16.3) |
Not done | 58 (39.5) |
Treatment | |
Pyridostigmine | 14 (9.5) |
Azathioprine | 4 (2.7) |
Pyridostigmine, prednisolone, with or without azathioprine | 94 (63.9) |
Pyridostigmine, prednisolone, with or without azathioprine, and one dose IVIg | 10 (6.8) |
Pyridostigmine, prednisolone, and mycophenolate | 11 (7.5) |
Pyridostigmine, prednisolone, with or without azathioprine, and monthly IVIg | 14 (9.5) |
Thymectomy | |
Done | 92 (62.6) |
Not done | 55 (37.4) |
Treatment response | |
Controlled | 101 (68.7) |
Not controlled | 46 (31.3) |
CT chest | |
Prominent thymus | 30 (20.4) |
Thymoma | 17 (11.6) |
Normal | 100 (68.0) |
Histopathology | |
Thymic hyperplasia | 57 (38.8) |
Thymoma | 13 (8.8) |
Normal | 22 (15) |
Clinical state at the end of follow up | |
Ocular | 7 (4.8) |
Bulbar | 4 (2.7) |
Generalized | 136 (92.5) |
Family history of MG | |
Positive | 6 (4.1) |
Negative | 95 (64.6) |
Not recorded | 46 (31.3) |
MG- Myasthenia gravis, AChR-acetylcholine receptors, RNS - repetitive nerve stimulation