- Pediatric sleep disorders pharmacotherapy.
Disease / Drug | Potential side effects |
---|---|
Chronic insomnia | |
Melatonin | Headache, dizziness, bed-wetting |
Antihistamines (diphenhydramine) | Dizziness, increase in the thickness of lung secretions |
Narcolepsy | |
Methylphenidate | Loss of appetite, suppression of growth, exacerbation of anxiety, nervousness, |
Dextroamphetamine, amphetamine- dextroamphetamine mixture | Loss of appetite, suppression of growth, exacerbation of anxiety, nervousness |
Modafinil, armodafinil | Headache, precipitation of Stevens-Johnson syndrome, decreases the potency of concurrently administered oral contraceptives |
Sodium oxybate | Tremor, constipation, bed-wetting, exacerbation of sleep apnea, weight loss, exacerbation of depression |
Cataplexy | |
Sodium oxybate | Tremor, constipation, bed-wetting, exacerbation of sleep apnea, weight loss, exacerbation of depression |
Venlafaxine, protriptyline, clomipramine | Drowsiness, weight gain, tremor |
Fluoxetine, sertraline | Nervousness, insomnia, increased risk of suicidal thoughts |
Restless leg syndrome | |
Elemental iron | onstipation and abdominal discomfort |
Gabapentin | Drowsiness, nausea |
Clonazepam | Drowsiness, tolerance |
Obstructive sleep apnea | |
Mild to moderate OSA: intranasal corticosteroids plus | Nasal irritation |
leukotriene inhibitor (montelukast). | Nausea, headache, dizziness |
Non-REM sleep parasomnias | |
Clonazepam | Drowsiness, tolerance |
L-5-hydroxytryptophan | Nausea |
Circadian sleep-wake disorders | |
Melatonin | Headache, dizziness, bed-wetting |