Table 2

- Types of skin manifestations and their clinical implications.

Types of skin disordersPrevalenceLocationPossible clinical treatmentsReferences
Seborrheic dermatitis18.6%–59%It is mainly located in areas rich in sebum, such as the scalp, face, upper chest, and skin layer under the arms and legs.Topical therapy:
  • - Ketoconazole shampoo

  • - Topical immune suppressants

(48)
Rosacea18.8%cheeks, nose, chin, forehead, or eyelids.Systemic therapy:
  • - Metronidazole

  • - Topical and systemic (non-immunosuppressive) therapies.

  • - Device/surgery-based therapies.

(39, 49)
Sweating disordershyperhidrosis 38%Affects the palms, soles, underarms, and sometimes the face.Increase sweating can be treated with:
  • - Dopaminergic therapy

  • - Reduction of the (OFF time) period

  • - Long-term subcutaneous apomorphine

  • - Intrajejunal levodopa infusion

  • - Intradermal injection of botulinum toxin.

(50)
hypohidrosis 15%
Bullous pemphigoid2.3%–17.9%Affects the lower abdomen, upper thighs, or armpits.
  • - Topical corticosteroids or oral doxycycline.

  • - Systemic corticosteroids alone or in combination with adjunctive immune-suppressing or modulating therapies.

(41)