- Clinical data of the 21 NF1 patients in 10 families.
| Pedigree number | Skinfold freckling | Cutaneous Neurofibromas | Plexiformneurofibromas | Lisch nodules | Optic glioma | Osseous lesions | Other tumors or cardiovascular defects | Intellectual disability |
|---|---|---|---|---|---|---|---|---|
| 1 | NA | - | - | - | - | - | - | - |
| 2 | NA | - | - | - | - | - | - | - |
| 3 | NA | - | - | - | - | - | Glioma | - |
| Yes | Yes | - | - | - | - | - | - | |
| NA | - | - | - | - | - | - | - | |
| Yes | Yes | - | - | - | - | - | - | |
| 4 | - | Yes | - | - | - | - | - | - |
| - | Yes | - | - | - | - | - | - | |
| 5 | Yes | Yes | - | - | - | - | - | - |
| - | Yes | - | - | - | - | - | - | |
| 6 | - | Yes | - | - | - | - | - | - |
| Yes | Yes | - | - | - | - | - | - | |
| 7 | - | Yes | - | - | - | - | - | - |
| - | Yes | - | - | - | - | - | - | |
| - | Yes | - | - | - | - | - | - | |
| - | Yes | - | - | - | - | - | - | |
| 8 | - | Yes | - | - | - | - | - | - |
| - | Yes | - | - | - | - | Intracranial aneurysm | Cognition impairment | |
| 9 | - | Yes | - | - | - | - | - | - |
| - | Yes | - | - | - | - | - | - | |
| 10 | - | Yes | - | - | - | - | Epilepsy | - |
CALMs, café-au-lait macules; NA, not available; -, none