Table 2

- Change in left ONSD measurements by time.

TimeMedian (Min-Max)P-value*
T1 ONSD4.4 (3.9-5.7)<0.001a
T2 ONSD4.1 (3.6-5.2)
T3 ONSD5.3 (4.2-6.0)
T4 ONSD4.3 (3.5-5.2)
T5 ONSD4.5 (3.9-5.8)
T1 ETD22.0 (20.0-25.3) 5.3<0.001b
T2 ETD22.0 (19.2-24.8) 5.6
T3 ETD22.0 (19.5-24.0)
T4 ETD22.0 (20.0-24.5) 4.5
T5 ETD22.0 (19.5-25.3) 5.8
T1 ONSD/ETD ratio0.20 (0.17-0.25)<0.001c
T2 ONSD/ETD ratio0.19 (0.16-0.24) 
T3 ONSD/ETD ratio0.24 (0.19-0.27) 
T4 ONSD/ETD ratio0.19 (0.17-0.24) 
T5 ONSD/ETD ratio0.21 (0.18-0.27) 

ONSD, optic nerve sheath diameter; ETD, eyeball transverse diameter,

  • * Freidman test.

  • ↵a Post hoc comparisons: All significant, except for paired comparison of T1-T5,

  • ↵b Post hoc comparisons: Paired comparisons of T1-T2, T1-T4, and T1-T5 are significant,

  • ↵c Post hoc comparisons: All significant. except for paired comparisons of T1-T4 and T2-T4