Characteristics | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 | Case 8 |
---|---|---|---|---|---|---|---|---|
Author (yr) | Regev I(1982) | Regev I(1982) | Carlander B(1991) | Kizilay F(2008) | Kung SL(2009) | Wang JY(2011) | Hsieh MY(2013) | Zhang J(2013) |
Population | Israel | Israel | France | USA | Taiwan/China | China | Taiwan/China | China |
Gender | F | F | M | M | F | M | F | M |
Age | 60 | 29 | 45 | 52 | 36 | 42 | 17 | 73 |
Preceding factors | - | - | + | + | + | + | + | + |
Clinical characteristics | Limb weakness, areflexia, ptosis, dyspnea, facial palsy | Limb weakness, areflexia, facial palsy, dysphagia, ptosis, dyspnea | Limb weakness, areflexia, facial palsy, ptosis, respiratory failure | Limb weakness, areflexia, ptosis, ophthalmoplegia | Limb weakness, areflexia, ptosis, ophthalmoplegia, facial palsy, dysarthria, respiratory failure | Limb weakness, areflexia, ptosis, ophthalmoplegia | Limb weakness, areflexia, ptosis, dysphagia, dysarthria, respiratory failure | Mild dyspnea, mild dysarthria and dysphagia, intubation, ptosis and weakness, |
Albumino-cytologic dissociation | - | - | + | + | + | + | + | - |
Nerve conduction | + | + | + | + | + | + | + | + |
RNS | - | - | + | + | + | + | + | + |
Anti-AChR antibody | + | + | + | + | + | + | + | + |
Anti-GQ1b antibody | - | - | - | - | - | - | - | - |
Edrophonium chloride | + | + | + | + | - | - | + | + |
Treatment | - | - | Pyridostigmine | IVIG, steroids, pyridostigmine | Plasma exchange, Pyridostigmine, steroids | IVIG, steroids, pyridostigmine, azathioprinum | IVIG, steroids, pyridostigmine | pyridostigmine, IVIG, methylprednisolone |
Thymectomy | - | + | + | - | - | - | + | - |
Prognosis | - | - | 6 | 3 | 1 | 0 | 0 | 4 |
MG - Myasthenia gravis, AIDP - Acute inflammatory demyelinating polyradiculoneuropathy, IVIG - intravenous immunoglobulin, RNS - repetitive nerve stimulation, Functional outcome was ranked according to the adopted scale by Hughes: 0 healthy; 1 minor symptoms or signs, able to run; 2 able to walk >5 m without assistance, but unable to run; 3 able to walk >5 m with assistance; 4 bed- or chair-bound; 5 requiring assisted ventilation for at least part of the day; and 6 dead. “+” indicates the patient had precipitating factors from infectious disease. “-” indicates the patient did not have precipitating factors from infectious disease. As for the other parameters, “+” indicates positive findings, and “-” indicates negative findings.