Summary of the neuroprotective effect of TQ against MPP+ treatment in primary mesencephalic cell culture.
| Studied parameters | Untreated controls | MPP+(10 μM) | TQ + MPP+(10 μM) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.01 μM | 0.1 μM | 1 μM | 10 μM | |||||||||
| % | SEM | % | SEM | % | SEM | % | SEM | % | SEM | % | SEM | |
| THir neurons | 100 | 3.00 | 60.80# | 4.50 | 66.83 | 3.01 | 69.64* | 3.39 | 71.24+ | 2.88 | 67.99 | 3.17 |
| LDH release | 100 | 13.50 | 245.99# | 30.76 | - | - | 175.40* | 16.95 | 169.52+ | 16.22 | - | - |
| LysoTracker® Deep Redintensity | 100 | 8.75 | 222.52# | 16.51 | - | - | - | - | 682.90* | 73.92 | - | - |
| JC-1 red/green fluorescence ratio | 100 | 2.08 | 83.92# | 3.16 | - | - | - | - | 107.18* | 2.99 | - | - |
| DAPI-stained apoptotic nuclei | 100 | 10.34 | 239.77# | 12.88 | - | - | - | - | 139.20* | 8.81 | - | - |