Structural, functional, and metabolic changes in the occipital lobe summary of the study by Steen et al.70
| Changes in the occipital lobe | Evidence for occipital alterations in schizophrenia |
|---|---|
| Structural changes | Reduction in the white matter integrity of the occipital cortex and fusiform gyrus in schizophrenia as compared to controls |
| A higher frequency of reverse asymmetry in the occipital lobe in schizophrenics | |
| No significant change in occipital lobe volume over time in schizophrenia compared to controls | |
| Functional changes | Moderate evidence suggests people with schizophrenia demonstrate reduced activity in the middle occipital gyrus during executive function tasks |
| Moderate quality evidence shows decreased functional activity in the fusiform gyrus and right lingual gyrus during memory encoding, and memory retrieval in schizophrenic patients compared to controls | |
| Moderate quality evidence shows that schizophrenic patients show decreased activation during emotion processing tasks in the fusiform, lentiform and middle occipital gyri | |
| Metabolic changes | Metabolic changes considering N-Acetyl Aspartate were found in the occipital lobe in schizophrenic patients |