Allelic frequency of CYP2C19 polymorphism among stroke patients.
Genes | Polymorphism | Allelic frequency of clopidogrel non responders n=25 | Allelic frequency of clopidogrel responders n=25 | Allelic chi-square value | P-value | Odds ratio and 95% CI |
---|---|---|---|---|---|---|
CYP2C19*2 | 681 G>A | G=0.62 A=0.38 | G=0.90 A=0.10 | Non responders vs responders: 21.49 | 0.00036 | 5.52 (2.42-12.83)* |
CYP2C19*3 | 636 G>A | G=0.68 A=0.32 | G=0.88 A=0.12 | Non responders vs responders:11.66 | 0.0006 | 3.45 (1.57-7.70)* |
vs - versus,
↵* significant