Genotypic Frequency of CYP2C19 polymorphism among stroke patients.
| Genes | Polymorphism | Genotypic frequency of clopidogrel non responders n=25 | Genotypic frequency of clopidogrel responders n=25 | Allelic chi-square value | P-value | Odds ratio and 95% CI |
|---|---|---|---|---|---|---|
| CYP2C19*2 | 681 G>A | GG=10 GA+AA=15 | GG=21 GA+AA=4 | Non responders Vs responders=10.27 | 0.001 | 7.88 (1.78-9.73)* |
| CYP2C19*3 | 636 G>A | GG=13 GA+AA=12 | GG=20 GA+AA=5 | Non responders Vs responders=4.37 | 0.036 | 3.69 (0.90-5.81)* |
Vs - versus, CI - confidence interval,
↵* significant