ADP induced platelet aggregation level by CYP2C19 polymorphisms in clopidogrel treated patients with ischemic stroke.
| Gene | Polymorphism | Genotypes | N=50 (non responders + responders group) | Platelet aggregation level |
|---|---|---|---|---|
| CYP2C19*2 | 681 G>A | GG (*1/*1) GA+AA (*1/*2,*2/*2) | 31 19 | 37.1±23.18 63.2±33.18 |
| CYP2C19*3 | 636 G>A | GG (*1/*1) GA+AA (*1/*3,*3/*3) | 33 17 | 43.1±27.18 58.29±28.18 |
Association between genotype and ADP-induced platelet aggregation (U) at p-value<0.05.