Gastrointestinal dysfunction in Parkinson's disease

Parkinsonism Relat Disord. 2011 Jan;17(1):10-5. doi: 10.1016/j.parkreldis.2010.08.003. Epub 2010 Sep 15.

Abstract

In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement.

Publication types

  • Review

MeSH terms

  • Constipation / etiology
  • Defecation / physiology
  • Deglutition Disorders / etiology
  • Gastrointestinal Diseases / etiology*
  • Gastrointestinal Diseases / physiopathology
  • Gastroparesis / etiology
  • Humans
  • Nausea / etiology
  • Parkinson Disease / complications*
  • Parkinson Disease / physiopathology
  • Sialorrhea / etiology
  • Tooth Diseases / etiology
  • Weight Loss