Open thrombectomy combined with thrombolysis in massive intracranial sinus thrombosis

Acta Neurochir (Wien). 1994;128(1-4):171-3. doi: 10.1007/BF01400670.

Abstract

A case of complete thrombosis of the superior sagittal sinus in a pregnant women with multiple haemorrhages and hydrocephalus is described. Due to acute onset and progressive neurological deterioration, the decision was taken to remove the clot surgically. A sinotomy was performed removing the thrombotic material followed by local infusion of tissue plasminogen activator (t-PA). The combination of surgical removal and thrombolysis was life-saving for this young patient.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cerebral Hemorrhage / etiology
  • Combined Modality Therapy
  • Female
  • Heparin / administration & dosage
  • Heparin / therapeutic use
  • Humans
  • Hydrocephalus / complications
  • Intracranial Pressure
  • Sinus Thrombosis, Intracranial / complications
  • Sinus Thrombosis, Intracranial / drug therapy*
  • Sinus Thrombosis, Intracranial / surgery*
  • Thrombectomy / methods*
  • Tissue Plasminogen Activator / administration & dosage
  • Tissue Plasminogen Activator / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Heparin
  • Tissue Plasminogen Activator