Are left atrial abnormalities a risk for stroke?

Neurosciences (Riyadh). 2010 Jan;15(1):21-6.

Abstract

Objectives: To show that echocardiographic left atrial enlargement (Echo-LAE) and electrocardiographic left atrial abnormalities (ECG-LAA) may be probable new risk factors for ischemic and hemorrhagic stroke.

Methods: This descriptive prospective case study included 140 CT or MRI-confirmed hemorrhagic and ischemic stroke patients, who were admitted to Rizgary Teaching Hospital, Erbil, Iraq from January 2008 to January 2009. Twelve lead ECG and 2-dimensional transthoracic Echo were performed for all patients. Electrocardiographic LAA were identified when the P terminal force in lead V1 (PTFV1) was >40 mm.ms. Echocardiographic LAE was identified when the left atrial index was more than 2.3 cm/m2.

Results: Electrocardiographic LAA we resignificantly higher in ischemic stroke patients in comparison with the hemorrhagic strokes. Causes of ECG-LAA were found to be as follows in order of frequency; hypertension (56%), advanced age (47%), coronary artery disease (27%), diabetes mellitus (26%), obesity (21%), valvular heart disease (21%), and 2.6% of patients had no identifiable cause. Echocardiographic-LAE was seen in 34% of ischemic strokes, and 30% of hemorrhagic strokes with no significant difference.

Conclusion: Although ECG-LAA (PTFV1>40 mm.ms) is significantly associated with ischemic stroke, it may not be an independent risk factor for stroke as it rarely occurred without other risk factors. Echocardiographic LAE i s associated with both ischemic and hemorrhagic strokes equally.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Electrocardiography / methods
  • Female
  • Heart Atria / pathology*
  • Heart Diseases / complications*
  • Humans
  • Hypertension / complications
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Stroke / diagnostic imaging
  • Stroke / etiology*
  • Stroke / pathology*
  • Tomography, X-Ray Computed / methods