The commercial potential of Aphanizomenon flos-aquae, a nitrogen-fixing edible cyanobacterium

GD Scoglio, HO Jackson, S Purton - Journal of Applied Phycology, 2024 - Springer
Aphanizomenon flos-aquae (AFA) is a Gram-negative nitrogen-fixing freshwater filamentous
cyanobacterium with a rich nutritional profile that is approved for human consumption by …

Neuroprotection in glaucoma: recent advances and clinical translation

C Guymer, JPM Wood, G Chidlow… - Clinical & …, 2019 - Wiley Online Library
Intraocular pressure (IOP) reduction is currently the only evidence‐based treatment strategy
for glaucoma. However, IOP control in some individuals is challenging. Despite optimal …

Treatment with erythropoietin for patients with optic neuritis: long-term follow-up

S Küchlin, G Ihorst, B Grotejohann, F Beisse… - Neurology …, 2023 - neurology.org
Background and Objective Erythropoietin (EPO) is a candidate neuroprotective drug. We
assessed its long-term safety and efficacy as an adjunct to methylprednisolone in patients …

Use of erythropoietin in ophthalmology: A review

S Feizi, M Alemzadeh-Ansari, F Karimian… - Survey of …, 2022 - Elsevier
Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human
body. The presence of EPO and its receptors in different tissues indicates that this hormone …

Revisiting the role of erythropoietin for treatment of ocular disorders

SL Shirley Ding, SN Leow, R Munisvaradass, EH Koh… - Eye, 2016 - nature.com
Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible
only in producing red blood cells in our body. However, with the discovery of the presence of …

Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease

C Donadei, A Angeletti, C Cantarelli, VD D'Agati… - JCI …, 2019 - pmc.ncbi.nlm.nih.gov
IL-17–producing CD4+ (Th17) cells are pathogenically linked to autoimmunity and,
specifically, to autoimmune kidney disease. The newly recognized immunoregulatory …

Safety and efficacy of erythropoietin for the treatment of patients with optic neuritis (TONE): a randomised, double-blind, multicentre, placebo-controlled study

WA Lagrèze, S Küchlin, G Ihorst… - The Lancet …, 2021 - thelancet.com
Background The human cytokine erythropoietin conveys neuroprotection in animal models
but has shown ambiguous results in phase 2 clinical trials in patients with optic neuritis. We …

Outbreak of methanol-induced optic neuropathy in early COVID-19 era; effectiveness of erythropoietin and methylprednisolone therapy

SA Tabatabaei, M Amini, AA Haydar… - World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
BACKGROUND Methanol is a highly toxic, non-potable alcohol. Outbreaks of methanol
toxicity occur due to its fraudulent addition to alcoholic beverages as a cheaper substitute for …

Current options for the treatment of optic neuritis

JH Pula, CJ MacDonald - Clinical Ophthalmology, 2012 - Taylor & Francis
Optic neuritis can be defined as typical (associated with multiple sclerosis, improving
independent of steroid treatment), or atypical (not associated with multiple sclerosis, steroid …

A double-blind, placebo-controlled trial of adding erythropoietin to intravenous methylprednisolone for the treatment of unilateral acute optic neuritis of unknown or …

V Shayegannejad, S Shahzamani, A Dehghani… - Graefe's Archive for …, 2015 - Springer
Purpose To compare the effect of adding recombinant human erythropoietin (rhEPO) to
intravenous methylprednisolone for the treatment of unilateral acute optic neuritis of …