Novel derivatives of quinazoline (1–27) have been synthesized and tested for their antitumor
activity against three tumor cell lines among these cell lines the human breast carcinoma …

Hepatocellular carcinoma accounts for about 80–90% of all liver cancer and is the fourth most
common cause of cancer mortality. Although there are many strategies for the treatment of …

Hypothyroidism induces cognitive impairment in experimental animals and patients. Clinical
reports are conflicting about the ability of thyroid hormone replacement therapy to fully …

Study Objectives: This study was undertaken to provide a detailed account of the effect of
chronic treatment with a small dose of caffeine on the deleterious effects of sleep loss on brain …

This study has been initiated to investigate whether endogenous carnitine depletion and/or
carnitine deficiency is a risk factor during development of cisplatin (CDDP)-induced …

It is well known that caffeine and sleep deprivation have opposing effects on learning and
memory; therefore, this study was undertaken to determine the effects of chronic (4wks) …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
increased deposition of beta-amyloid (Aβ) peptides and progressive cholinergic dysfunction in …

AIM: To investigate whether carnitine deficiency is a risk factor during the development of
diethylnitrosamine (DENA)-induced hepatic carcinogenesis. METHODS: A total of 60 male …

The testis is an immunologically privileged organ. Sertoli cells can form a blood-testis
barrier and protect sperm cells from self-immune system attacks. Spermatogenesis may be …

Objectives: Present study aims to investigate the ameliorative effects of naringenin (NG) on
experimentally induced diabetic neuropathy (DN) in rats. Methods: Diabetes was induced by …