Neurotrophins are secreted proteins that are synthesized as pre-pro-neurotrophins on the
rough endoplasmic reticulum, which are subsequently processed and then secreted as …

Cardiac diseases are the leading cause of mortality and morbidity worldwide. Mounting
evidence suggests that transglutaminases (TGs), tissue TG (TG2) in particular, are involved in …

Progesterone is a steroidal hormone that is produced from the corpus luteum of the ovaries
and from the placenta. The main function of progesterone is to promote the secretory …

Background. Insomnia is a problem that is common in all societies and age groups. However,
its importance is increasing between students especially with the highly competitive and …

Background Obesity and associated hormonal disturbances are risk factors for colon cancer.
Cytosolic Malic Enzyme (ME1) generates NADPH used for lipogenesis in gastrointestinal (…

Aims Transglutaminase (TG) inhibitors represent promising therapeutic interventions in
cardiac fibrosis and related dysfunctions. However, it remains unknown how TG inhibition, TG2 …

Transglutaminase (TG) isoforms control diverse normal and pathophysiologic processes
through their capacity to cross-link extracellular matrix (ECM) proteins. Their functional and …

The small intestine participates in lipid digestion, metabolism and transport. Cytosolic malic
enzyme 1 (ME1) is an enzyme that generates NADPH used in fatty acid and cholesterol …

Various gastrointestinal (GI) disorders have a higher prevalence in women than in men. In
addition, estrogen has been demonstrated to have an inhibitory effect on the contractility of GI …

Royal jelly (RJ) is a multifunctional bee product with a unique composition and wide-ranging
biological properties, including antioxidant, anti-inflammatory and antiproliferative activities. …