User profiles for Ajay Prakash

Dr. Ajay Prakash

Associate Professor of Pharmacology
Verified email at pgimer.edu.in
Cited by 7574

[HTML][HTML] Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential

…, RF Schwabe, JP Pradere, K Walton, A Prakash… - Cell, 2015 - cell.com
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model
suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, …

Serum ferritin as a predictive biomarker in COVID-19. A systematic review, meta-analysis and meta-regression analysis

…, A Kothari, S Kumar, S Rana, M Kaur, A Prakash… - Journal of critical …, 2022 - Elsevier
Ferritin is a known inflammatory biomarker in COVID-19. However, many factors and co-morbidities
can confound the level of serum ferritin. This current metaanalysis evaluates serum …

Virological and clinical cure in COVID‐19 patients treated with hydroxychloroquine: a systematic review and meta‐analysis

…, A Singh, DP Dhibar, A Prakash… - Journal of medical …, 2020 - Wiley Online Library
Following the demonstration of the efficacy of hydroxychloroquine against severe acute
respiratory syndrome coronavirus 2 in vitro, many trials started to evaluate its efficacy in clinical …

In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)

…, S Kumar, S Singh, H Kumar, A Prakash… - Journal of …, 2021 - Taylor & Francis
The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV)
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex, …

[HTML][HTML] Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes

…, N Shekhar, S Sharma, P Sarma, A Prakash… - Pharmacological …, 2021 - Springer
Introduction COVID-19 cases are on surge; however, there is no efficient treatment or vaccine
that can be used for its management. Numerous clinical trials are being reviewed for use …

Hedgehog-responsive mesenchymal clusters direct patterning and emergence of intestinal villi

…, MJ Czerwinski, MJ Bell, A Prakash… - Proceedings of the …, 2012 - National Acad Sciences
In the adult intestine, an organized array of finger-like projections, called villi, provide an
enormous epithelial surface area for absorptive function. Villi first emerge at embryonic day (E) …

Role of vinpocetine in cerebrovascular diseases

S Patyar, A Prakash, M Modi, B Medhi - Pharmacological Reports, 2011 - Springer
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit,
which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow …

[HTML][HTML] Rhino-orbital-cerebral-mucormycosis in COVID-19: A systematic review

…, S Kumar, S Bansal, A Prakash… - Indian journal of …, 2021 - journals.lww.com
Since the onset of COVID-19 pandemic, parallel opportunistic infections have also been
emerging as another disease spectrum. Among all these opportunistic infection, mucormycosis …

Recent advances in molecular pathways and therapeutic implications targeting mitochondrial dysfunction for Alzheimer's disease

R Dhapola, P Sarma, B Medhi, A Prakash… - Molecular …, 2022 - Springer
Alzheimer’s disease (AD) is a neurodegenerative disorder which leads to mental deterioration
due to aberrant accretion of misfolded proteins in the brain. According to mitochondrial …

[HTML][HTML] A comprehensive review of animal models for coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV

…, G Batra, R Joshi, H Kaur, AR Sharma, A Prakash… - Virologica Sinica, 2020 - Springer
The recent outbreak of coronavirus disease (COVID-19) caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has already affected a large population of …