This report describes the synthesis of L-and D-[methyl-11C] methionine in pure enantiomeric
forms. The compounds were prepared routinely approximately 1,000 times with less than …

New 11 C-labelled precursors [1- 11 C]ethyl, [1- 11 C]propyl, [1- 11 C]butyl, and [1- 11 C]isobutyl
iodides have been prepared by a 3-step reaction route using a one-pot system. The …

Positron emission tomography (PET) is a noninvasive technique for studies of the regional
kinetics of positron-emitting radiotracers. A drug or other molecule is labeled with short-lived …

The regional distribution and kinetics in the brain of Rhesus monkeys of N‐(methyl‐ 11 C)‐pethidine
have been studied by positron emission tomography, PET. C‐Pethidine reached …

The synthesis of N-[ methyl - 11 C] hydromorphone has been performed by using [ 11 C]methyl
iodide and desmethyl hydromorphone in a mixture of dimethylsulphoxide and …

The regional brain kinetics of the opioid receptor agonist, hydromorphone, labelled with 11
C, were studied with positron emission tomography in two Macaque species, Rhesus and …

All analytical activities require work of a high standard that is accurately documented. For
this purpose, most laboratories carry out some form of internal quality assurance, but their …

All analytical activities require the maintenance of a work at high standard and well documented.
For this purpose most laboratories practice some internal quality assurance, but the …

… is taken by the Rimland (the costal or peripheral/Rimland zone). The Rimland zone is a broad
… Spykman states: “Who controls the Rimland rules Eurasia; who rules Eurasia controls the …

… The Western strategy of the Cold War was a rimland strategy for containment of the USSR
by a string of military alliances around the Eurasian Soviet core – ranging from NATO in the …