Final results of the RHAPSODY trial: a multi‐center, phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A‐APC, a …

…, S Song, P Hannon, NS Rost, A Hinduja… - Annals of …, 2019 - Wiley Online Library
Objective Agonism of protease‐activated receptor (PAR) 1 by activated protein C (APC)
provides neuro‐ and vasculoprotection in experimental neuroinjury models. The pleiotropic …

[HTML][HTML] Posterior reversible encephalopathy syndrome: clinical features and outcome

A Hinduja - Frontiers in neurology, 2020 - frontiersin.org
Background: Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic
syndrome that is characterized by a spectrum neurological and radiological feature from …

Neuroinflammation in acute ischemic and hemorrhagic stroke

…, K Bhatia, J Biller, S Andalib, A Hinduja… - Current Neurology and …, 2023 - Springer
Purpose of Review This review aims to provide an overview of neuroinflammation in ischemic
and hemorrhagic stroke, including recent findings on the mechanisms and cellular players …

Perfusion imaging predicts favorable outcomes after basilar artery thrombectomy

…, M Mlynash, N Yuen, AY Qureshi, A Hinduja… - Annals of …, 2022 - Wiley Online Library
Objective Perfusion imaging identifies anterior circulation stroke patients who respond
favorably to endovascular thrombectomy (ET), but its role in basilar artery occlusion (BAO) is …

Nosocomial infections in patients with spontaneous intracerebral hemorrhage

A Hinduja, J Dibu, E Achi, A Patel, R Samant… - American Journal of …, 2015 - AACN
Background Nosocomial infections are frequent complications in patients with intracerebral
hemorrhage. Objectives To determine the prevalence, risk factors, and outcomes of …

Contemporary antiplatelet and anticoagulant therapies for secondary stroke prevention: a narrative review of current literature and guidelines

…, DL Alsbrook, A Hinduja… - Current Neurology and …, 2023 - Springer
Purpose of Review Stroke is a leading cause of death and disability worldwide. The annual
incidence of new or recurrent stroke is approximately 795,000 cases per year in the United …

[HTML][HTML] Pathophysiology of early brain injury and its association with delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a review of current …

…, M Di Napoli, K Bhatia, M Desai, A Hinduja… - Journal of Clinical …, 2023 - mdpi.com
Background: Delayed cerebral ischemia (DCI) is a common and serious complication of
aneurysmal subarachnoid hemorrhage (aSAH). Though many clinical trials have looked at …

Role of admission serum albumin levels in patients with intracerebral hemorrhage

K Limaye, JD Yang, A Hinduja - Acta Neurologica Belgica, 2016 - Springer
Low serum albumin levels have been reported to be an independent predictor of increased
morbidity and mortality in multiple disease conditions. The aim of our study was to identify …

Predictors of poor outcome in patients with posterior reversible encephalopathy syndrome

A Hinduja, K Habetz, S Raina… - International Journal …, 2017 - Taylor & Francis
Purpose: Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic
syndrome that, although characteristically reversible, can be fatal or result in long-term disability …

Hematoma expansion in spontaneous intracerebral hemorrhage: predictors and outcome

…, E Achi, A Patel, R Samant, A Hinduja - International Journal …, 2014 - Taylor & Francis
Background: Hematoma growth is an independent determinant of outcome in patients with
intracerebral hemorrhage (ICH). Predictors of hematoma expansion are poorly defined. Our …