[HTML][HTML] Neuroprotective effects of emodin against ischemia/reperfusion injury through activating ERK-1/2 signaling pathway

…, YH Chen, SJ Kang, YH Chiang, CF Chang… - International journal of …, 2020 - mdpi.com
Background: Stroke is one of the leading causes of death and disability worldwide and
places a heavy burden on the economy in our society. Current treatments, such as the use of …

Inhibition of zinc metallopeptidases in cardiovascular disease-from unity to trinity, or duality?

V Dive, CF Chang, A Yiotakis… - Current pharmaceutical …, 2009 - ingentaconnect.com
The fusion of therapeutics and diagnostic medicine in an effort to provide individualized
pharmacotherapy frequently requires the manipulation of drugs that target different enzymes and …

[HTML][HTML] Successful treatment of Dandy–Walker syndrome by endoscopic third ventriculostomy in a 6-month-old girl with progressive hydrocephalus: a case report and …

CF Hu, HC Fan, CF Chang, CC Wang, SJ Chen - Pediatrics & Neonatology, 2011 - Elsevier
Dandy–Walker syndrome (DWS) is a congenital brain malformation involving the cerebellum
and fourth ventricle. We report a 6-month-old girl with DWS presenting an initially normal …

[HTML][HTML] Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS

CF Chang, YC Lee, KH Lee, HC Lin, CL Chen… - Journal of biomedical …, 2016 - Springer
Background In the central nervous system regions of the sporadic and familial FTLD and ALS
patients, TDP-43 has been identified as the major component of UBIs inclusions which is …

[HTML][HTML] Psychometric evaluation of anxiety, depression, and sleep quality after a mild traumatic brain injury: a longitudinal study

HP Ma, PS Chen, CS Wong, CF Chang, JC Ou… - Behavioural …, 2019 - hindawi.com
Introduction. Over 1 million mild traumatic brain injury (mTBI) cases are reported annually
worldwide and may result in cognitive, physical, and emotional deterioration; depression; …

(−)-Phenserine inhibits neuronal apoptosis following ischemia/reperfusion injury

CF Chang, JH Lai, JCC Wu, NH Greig, RE Becker… - Brain research, 2017 - Elsevier
Stroke commonly leads to adult disability and death worldwide. Its major symptoms are spastic
hemiplegia and discordant motion, consequent to neuronal cell death induced by brain …

[HTML][HTML] Pomalidomide Ameliorates H2O2-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and …

YR Tsai, CF Chang, JH Lai, JCC Wu, YH Chen… - International Journal of …, 2018 - mdpi.com
Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the
brain is particularly vulnerable to oxidative stress. Induced by a redox state imbalance …

[HTML][HTML] Current approaches to the treatment of head injury in children

CF Hu, HC Fan, CF Chang, SJ Chen - Pediatrics & Neonatology, 2013 - Elsevier
Head trauma is one of the most challenging fields of traumatology and demands immediate
attention and intervention by first-line clinicians. Symptoms can vary from victim to victim and …

Glucose-dependent insulinotropic polypeptide ameliorates mild traumatic brain injury-induced cognitive and sensorimotor deficits and neuroinflammation in rats

…, BJ Hoffer, NH Greig, Y Li, JH Lai, CF Chang… - Journal of …, 2016 - liebertpub.com
Mild traumatic brain injury (mTBI) is a major public health issue, representing 75–90% of all
cases of TBI. In clinical settings, mTBI, which is defined as a Glascow Coma Scale (GCS) …

[HTML][HTML] Fabrication of Implantable, Enzyme-Immobilized Glutamate Sensors for the Monitoring of Glutamate Concentration Changes in Vitro and in Vivo

TTC Tseng, CF Chang, WC Chan - Molecules, 2014 - mdpi.com
Cheng-Fu Chang designed and performed research and analyzed the data. Wen-Chin
Chan performed research and analyzed the data. All authors read and approved the final …