User profiles for Cyril Cyrus
 | Cyril CyrusImam Abdulrahman Bin Faisal University Verified email at iau.edu.sa Cited by 1639 |
Cytogenetic evaluation of down syndrome: A review of 1020 referral cases
A retrospective analysis was performed on 1102 cases with a provisional diagnosis of Down
syndrome referred to the Department of Genetics, Dr.ALMPGIBMS, University of Madras …
syndrome referred to the Department of Genetics, Dr.ALMPGIBMS, University of Madras …
Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
Chronic mucocutaneous candidiasis (CMC) is defined as recurrent or persistent infection of
the skin, nails, and/or mucosae with commensal Candida species. The first genetic etiology …
the skin, nails, and/or mucosae with commensal Candida species. The first genetic etiology …
[HTML][HTML] The role of miRNAs as therapeutic tools in sickle cell disease
C Cyrus - Medicina, 2021 - mdpi.com
Background and Objectives: Sickle cell disorder (SCD) is a paradigmatic example of a complex
monogenic disorder. SCD is characterized by the production of abnormal hemoglobin, …
monogenic disorder. SCD is characterized by the production of abnormal hemoglobin, …
[HTML][HTML] Association of Uncoupling Protein 1 (UCP1) gene polymorphism with obesity: a case-control study
Background Obesity is one of the main causes of morbidity and mortality worldwide. More
than 120 genes have been shown to be associated with obesity related phenotypes. The aim …
than 120 genes have been shown to be associated with obesity related phenotypes. The aim …
[HTML][HTML] MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India
BACKGROUND: The 5, 10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms
and low folate levels are associated with inhibition of DNA methyltransferase and …
and low folate levels are associated with inhibition of DNA methyltransferase and …
[HTML][HTML] Bedside testing of CYP2C19 vs. conventional clopidogrel treatment to guide antiplatelet therapy in ST-segment elevation myocardial infarction patients
Background ST-segment elevation myocardial infarction (STEMI) patients are treated with
dual antiplatelet therapy comprising aspirin and a P2Y 12 inhibitor. Clopidogrel is widely used …
dual antiplatelet therapy comprising aspirin and a P2Y 12 inhibitor. Clopidogrel is widely used …
Tyrosine kinase domain mutations of EGFR gene in head and neck squamous cell carcinoma
Background Epidermal growth factor receptor (EGFR) is a commonly altered gene that is
identified in various cancers, including head and neck squamous cell carcinoma (HNSCC). …
identified in various cancers, including head and neck squamous cell carcinoma (HNSCC). …
[HTML][HTML] Oral microbiota analyses of paediatric Saudi population reveals signatures of dental caries
…, L Hamilton, D Gandla, H Lad, FL Robinson, C Cyrus… - BMC Oral Health, 2023 - Springer
Background Oral microbiome sequencing has revealed key links between microbiome
dysfunction and dental caries. However, these efforts have largely focused on Western …
dysfunction and dental caries. However, these efforts have largely focused on Western …
Elevated fibroblast growth factor 23 concentration: prediction of mortality among chronic kidney disease patients
Background: The osteocyte-derived hormone, fibroblast growth factor 23 (FGF23), regulates
the phosphorus metabolism and suppresses 1, 25-dihydroxyvitamin D production, thereby …
the phosphorus metabolism and suppresses 1, 25-dihydroxyvitamin D production, thereby …
Analysis of the Impact of Common Polymorphisms of the FTO and MC4R Genes with the Risk of Severe Obesity in Saudi Arabian Population
Background: Obesity has reached epidemic proportions worldwide resulting in a serious
public health problem. In Saudi Arabia, 28.7% of the population is obese due largely to the …
public health problem. In Saudi Arabia, 28.7% of the population is obese due largely to the …