Calcification and ossification of the convexity of the falx cerebri and related subdural space in human cadavers
OBJECTIVE: The present work was planned to report the incidence of calcification and
ossification of an isolated cranial dural fold. The form, degree of severity and range of extension …
ossification of an isolated cranial dural fold. The form, degree of severity and range of extension …
Synthesis of some novel 4-benzothiazol-2-yl-benzoyl-1H-pyrazoles, and evaluation as antiangiogenic agents
EAA El-Meguid, MM Ali - Research on Chemical Intermediates, 2016 - Springer
Some 4-(1,3-benzothiazol-2-yl)-benzoyl-1H-pyrazole derivatives have been synthesized by
reaction of o-aminothiophenol (1) with different electrophilic and nucleophilic reagents. All of …
reaction of o-aminothiophenol (1) with different electrophilic and nucleophilic reagents. All of …
Novel benzothiazole-based dual VEGFR-2/EGFR inhibitors targeting breast and liver cancers: Synthesis, cytotoxic activity, QSAR and molecular docking studies
EA Abd El-Meguid, AM Naglah, GO Moustafa… - Bioorganic & Medicinal …, 2022 - Elsevier
A novel series of benzothiazole-based derivatives linked to various amino acids and their
corresponding ethyl ester analogues were prepared and were initially evaluated for their …
corresponding ethyl ester analogues were prepared and were initially evaluated for their …
Novel benzothiazole hybrids targeting EGFR: Design, synthesis, biological evaluation and molecular docking studies
EA Abd El-Meguid, GO Moustafa, HM Awad… - Journal of Molecular …, 2021 - Elsevier
Novel benzo[d] thiazole-based analogues were synthesized with the aim of screening their
in vitro anticancer activity. All the new derivatives 4–21 were evaluated against human …
in vitro anticancer activity. All the new derivatives 4–21 were evaluated against human …
[HTML][HTML] Synthesis, docking studies, and in vitro evaluation of some novel thienopyridines and fused thienopyridine–quinolines as antibacterial agents and DNA …
EM Mohi El-Deen, EA Abd El-Meguid, S Hasabelnaby… - Molecules, 2019 - mdpi.com
A series of novel thienopyridines and pyridothienoquinolines (3a,b–14) was synthesized,
starting with 2-thioxo-1,2-dihydropyridine-3-carbonitriles 1a and 1b. All compounds were …
starting with 2-thioxo-1,2-dihydropyridine-3-carbonitriles 1a and 1b. All compounds were …
[HTML][HTML] Novel benzimidazole derivatives as anti-cervical cancer agents of potential multi-targeting kinase inhibitory activity
EA Abd El-Meguid, EMM El-Deen, MA Nael… - Arabian Journal of …, 2020 - Elsevier
Multi-target EGFR, HER2, VEGFR-2 and PDGFR is an improved strategy for the treatment of
solid tumors. This work deals with synthesis of an array of new 6-benzoyl benzimidazole …
solid tumors. This work deals with synthesis of an array of new 6-benzoyl benzimidazole …
[HTML][HTML] Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors
EM Mohi El-Deen, EA Abd El-Meguid, EA Karam… - Antibiotics, 2020 - mdpi.com
The growing resistance of bacteria to many antibiotics that have been in use for several
decades has generated the need to discover new antibacterial agents with structural features …
decades has generated the need to discover new antibacterial agents with structural features …
Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer
HT Abdel‐Mohsen, EA Abd El‐Meguid… - Archiv der …, 2020 - Wiley Online Library
A novel series of 2‐arylbenzothiazoles 9, 10, and 12 were designed and synthesized as
VEGFR‐2/FGFR‐1/PDGFR‐β multiangiokinase inhibitors targeting breast cancer. Structural …
VEGFR‐2/FGFR‐1/PDGFR‐β multiangiokinase inhibitors targeting breast cancer. Structural …
Novel 2-arylbenzothiazole DNA gyrase inhibitors: Synthesis, antimicrobial evaluation, QSAR and molecular docking studies
A series of new 2-arylbenzothiazole derivatives (4, 5, 6a-j, 7a-i and 8a,b) was synthesized
and tested for their antimicrobial activity against different Gram-positive, Gram-negative …
and tested for their antimicrobial activity against different Gram-positive, Gram-negative …
Synthesis and anticancer activity of novel 2-substituted pyranopyridine derivatives
SF Mohamed, ER Kotb, EA Abd El-Meguid… - Research on Chemical …, 2017 - Springer
A novel series of 2-aminopyranopyridine derivatives (3–19) were synthesized utilizing 2-chloro-4-(thiophen-2-yl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile
(2) as a key …
(2) as a key …