Background Generalized pustular psoriasis is a life-threatening disease of unknown cause.
It is characterized by sudden, repeated episodes of high-grade fever, generalized rash, and …

We aimed in the first part of our work to study the effect of cryopreservation on the human
sperm DNA integrity and the activation of caspase 3, the main apoptosis indicator. In the …

Background There is clinical evidence to show that sperm DNA damage could be a marker
of sperm quality and extensive data exist on the relationship between DNA damage and …

The congenital muscular dystrophies (CMD) constitute a clinically and genetically
heterogeneous group of autosomal recessive myopathies. Patients show congenital hypotonia, …

Purpose To assess the incidence and the type of chromosomal aberrations in males with
infertility we reviewed cytogenetic results in 76 Tunisian infertile men (54 nonobstructive …

In this study we performed a systematic sequence analysis of 6 mitochondrial genes (cytochrome
oxidase I, cytochrome oxidase II, cytochrome oxidase III, adenosine triphosphate …

Diabetes mellitus (DM) is a heterogeneous disorder characterized by the presence of chronic
hyperglycemia. Genetic factors play an important role in the development of this disorder, …

Mitochondrial diabetes (MD) is a heterogeneous disorder characterized by a chronic
hyperglycemia, maternal transmission and its association with a bilateral hearing impairment. …

Introduction Leptin (LEP) gene is one of the most promising candidate genes for obesity.
Previous studies have tested the association of polymorphisms in LEP gene with obesity and …

Pustular psoriasis of pregnancy (PPP) can lead to life‐threatening complications. The
objective of this study is to report clinical and genetic spectrum, prognostic factors and …