Tumor necrosis factor-alpha (TNF-α)− 238 G/A polymorphism is associated with the treatment resistance and attempted suicide in schizophrenia

HM Aytac, K Ozdilli, FC Tuncel, M Pehlivan… - Immunological …, 2022 - Taylor & Francis
Abnormality of the immune system may play an important role in the pathogenesis of
schizophrenia (SCZ). We aim to investigate the relationship between clinical features of SCZ and …

[HTML][HTML] Interleukin-1 receptor antagonist (IL-1RA) and interleukin-4 (IL-4) variable number of tandem repeat polymorphisms in schizophrenia and bipolar disorder: an …

S Pehlivan, Y Oyaci, FC Tuncel, HM Aytac - Egyptian Journal of Medical …, 2022 - Springer
Background Pro-inflammatory/anti-inflammatory cytokine imbalance in cerebrospinal fluid
or plasma of schizophrenia (SCZ) and bipolar disorder (BD) patients has been documented …

[HTML][HTML] Epigenetic and genetic investigation of SOCS-1 gene in patients with multiple myeloma

FC Tuncel, I Serin, S Pehlivan, Y Oyaci… - Blood research, 2022 - ncbi.nlm.nih.gov
Background The suppressor of cytokine signaling-1 (SOCS-1) functions to induce an
appropriate immune response and is an essential physiological regulator of interferon signaling. …

The effect of mesenchymal stem cells administration on DNA repair gene expressions in critically ill COVID-19 patients: prospective controlled study

…, D Irmak Koyuncu, FC Tuncel… - … Nucleotides & Nucleic …, 2024 - Taylor & Francis
When the studies are evaluated, immunomodulatory effect of MSCs, administration in
critically ill patients, obstacle situations in use and side effects, pulmonary fibrosis prevention, …

IL2RA rs2104286 and IL2 rs2069762 polymorphisms may be associated with bipolar disorder and its clinical findings

…, HM Aytac, AF Nursal, FC Tuncel… - … Nucleotides & Nucleic …, 2024 - Taylor & Francis
Study results supported that immuno-inflammatory pathways in the brain and environment
contribute to the etiopathogenesis of bipolar disorder (BD), a chronic affective disease. Our …

Effect of interleukin-2 (IL-2) polymorphisms on multiple myeloma: IL-2RA rs2104286, IL-2 rs2069762 and rs2069763 polymorphisms

I Serin, Y Colak, Y Oyaci, FC Tuncel, M Pehlivan… - Cytokine, 2023 - Elsevier
Interleukin-2 (IL-2) is a cytokine secreted from T helper type 1 cells and released after
induction of T helper cells with major histocompatibility complexes or antigens presented by …

Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population

K Ozdilli, HM Aytac, FC Tuncel, Y Oyaci… - Neurosciences …, 2024 - nsj.org.sa
Objectives: To evaluate the genetic polymorphisms in IL-2 and IL-2RA genes in schizophrenia
(SCZ) patients by comparing them with healthy controls. Methods: A sample of 127 …

[PDF][PDF] PARKİNSON HASTALIĞINDA ALFA SİNÜKLEİN FİBRİLLERİNİN AKSONAL TRANSPORTU

FC Tunçel, BA Arslan - 2019 - researchgate.net
Neurodegenerative diseases are characterized by progressive and irreversible loss of neurons
in the central nervous system (CNS) over time. The most important symptom of Parkinson’…

PB1968: EPIGENETIC AND GENETIC INVESTIGATION OF SOCS-1 GENE IN PATIENTS WITH MULTIPLE MYELOMA

I Serin, FC TUNCEL, S PEHLIVAN, Y OYACI… - …, 2022 - journals.lww.com
Background: The suppressor of cytokine signaling-1 (SOCS-1) functions to induce an
appropriate immune response and is an essential physiological regulator of interferon signaling. …

[CITATION][C] BLOOD RESEARCH

FC Tuncel, I Serin, S Pehlivan, Y Oyaci, M Pehlivan - 2022 - europepmc.org
Background The suppressor of cytokine signaling-1 (SOCS-1) functions to induce an
appropriate immune response and is an essential physiological regulator of interferon signaling. …