The sequence of the human genome

…, H Zhang, Q Zhao, L Zheng, F Zhong, W Zhong… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Comparative genomics of the eukaryotes

…, J Zhang, Q Zhao, XH Zheng, F Zhong, W Zhong… - Science, 2000 - science.org
A comparative analysis of the genomes ofDrosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode—was …

Bcl-2 functionally interacts with inositol 1, 4, 5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1, 4, 5-trisphosphate

R Chen, I Valencia, F Zhong, KS McColl… - The Journal of cell …, 2004 - rupress.org
Inositol 1,4,5-trisphosphate (InsP 3 ) receptors (InsP 3 Rs) are channels responsible for calcium
release from the endoplasmic reticulum (ER). We show that the anti-apoptotic protein Bcl…

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome

…, XH Zheng, DR Nusskern, Z Lai, Y Lei, W Zhong… - Science, 2002 - science.org
The high degree of similarity between the mouse and human genomes is demonstrated
through analysis of the sequence of mouse chromosome 16 (Mmu 16), which was obtained as …

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

…, G Bultynck, AS Aromolaran, F Zhong… - Proceedings of the …, 2009 - National Acad Sciences
Although the presence of a BH4 domain distinguishes the antiapoptotic protein Bcl-2 from
its proapoptotic relatives, little is known about its function. BH4 deletion converts Bcl-2 into a …

[PDF][PDF] Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

YP Rong, AS Aromolaran, G Bultynck, F Zhong, X Li… - Molecular cell, 2008 - cell.com
The antiapoptotic protein Bcl-2 inhibits Ca 2+ release from the endoplasmic reticulum (ER).
One proposed mechanism involves an interaction of Bcl-2 with the inositol 1,4,5-…

Whole-genome shotgun assembly and comparison of human genome assemblies

…, BC Shue, XH Zheng, F Zhong… - Proceedings of the …, 2004 - National Acad Sciences
We report a whole-genome shotgun assembly (called WGSA) of the human genome
generated at Celera in 2001. The Celera-generated shotgun data set consisted of 27 million …

Myristoleic acid produced by enterococci reduces obesity through brown adipose tissue activation

…, C Yan, X Liu, H Zhou, H Zhang, L Chen, FL Zhong… - Gut, 2020 - gut.bmj.com
Objective Dietary fibre has beneficial effects on energy metabolism, and the majority of studies
have focused on short-chain fatty acids produced by gut microbiota. Ginseng has been …

Photocatalytic GO/M88A “interceptor plate” assembled nanofibrous membrane with photo-Fenton self-cleaning performance for oil/water emulsion separation

L Zhang, Y He, P Luo, L Ma, S Li, Y Nie, F Zhong… - Chemical Engineering …, 2022 - Elsevier
Developing the high-efficient and robust antifouling membranes for oily emulsions to achieve
the purpose of prolonging the service life of the membrane shows great demand because …

Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals

Z Wang, MH Malone, MJ Thomenius, F Zhong… - Journal of Biological …, 2003 - ASBMB
Glucocorticoid hormones induce apoptosis in lymphoid cells. This process requires de novo
RNA/protein synthesis. Here we report the identification and cloning of a novel …