User profiles for Gea A. Holtman

Gea Holtman

Rijksuniversiteit Groningen
Verified email at umcg.nl
Cited by 1226

[HTML][HTML] Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with high-grade glioma, a systematic review and …

BRJ van Dijken, PJ van Laar, GA Holtman… - European …, 2017 - Springer
Objective Treatment response assessment in high-grade gliomas uses contrast enhanced
T1-weighted MRI, but is unreliable. Novel advanced MRI techniques have been studied, but …

[HTML][HTML] Incidence of tumour progression and pseudoprogression in high-grade gliomas: a systematic review and meta-analysis

AW Abbasi, HE Westerlaan, GA Holtman… - Clinical …, 2018 - Springer
Background High-grade gliomas are the most common primary brain tumours.
Pseudoprogression describes the false appearance of radiation-induced progression on MRI. A …

Routine laboratory testing to determine if a patient has COVID‐19

…, EA Ochodo, F Guleid, GA Holtman… - Cochrane Database …, 1996 - cochranelibrary.com
Background Specific diagnostic tests to detect severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) and resulting COVID‐19 disease are not always available and take time …

Noninvasive tests for inflammatory bowel disease: a meta-analysis

GA Holtman, Y Lisman-van Leeuwen, JB Reitsma… - …, 2016 - publications.aap.org
BACKGROUND: The clinical presentation of pediatric inflammatory bowel disease (IBD) is
often nonspecific and overlaps with functional gastrointestinal disorders. OBJECTIVE: To …

Diagnostic accuracy of PET tracers for the differentiation of tumor progression from treatment-related changes in high-grade glioma: a systematic review and …

PL de Zwart, BRJ van Dijken, GA Holtman… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Posttreatment high-grade gliomas are usually monitored with contrast-enhanced MRI, but
its diagnostic accuracy is limited as it cannot adequately distinguish between true tumor …

Use of laboratory markers in addition to symptoms for diagnosis of inflammatory bowel disease in children: a meta-analysis of individual patient data

GA Holtman, Y Lisman-van Leeuwen, AS Day… - JAMA …, 2017 - jamanetwork.com
Importance Blood markers and fecal calprotectin are used in the diagnostic workup for
inflammatory bowel disease (IBD) in pediatric patients. Any added diagnostic value of these …

Diagnostic accuracy of fecal calprotectin for pediatric inflammatory bowel disease in primary care: a prospective cohort study

GA Holtman, Y Lisman-van Leeuwen… - The Annals of Family …, 2016 - Annals Family Med
PURPOSE In specialist care, fecal calprotectin (FCal) is a commonly used noninvasive
diagnostic test for ruling out inflammatory bowel disease (IBD) in children with chronic …

Dientamoeba fragilis colonization is not associated with gastrointestinal symptoms in children at primary care level

GA Holtman, JJ Kranenberg, MH Blanker, A Ott… - Family …, 2016 - academic.oup.com
Background. Dientamoeba fragilis is commonly identified in children in primary care and is
suspected to cause gastrointestinal disease. Objective. To determine the association …

Diagnostic accuracy of blood tests of inflammation in paediatric appendicitis: a systematic review and meta-analysis

…, A Van Den Bruel, JM Ordóñez-Mena, GA Holtman - BMJ open, 2022 - bmjopen.bmj.com
Objective Possible childhood appendicitis is a common emergency presentation. The exact
value of blood tests is debated. This study sought to determine the diagnostic accuracy of …

Development of practical recommendations for diagnostic accuracy studies in low-prevalence situations

GA Holtman, MY Berger, H Burger, JJ Deeks… - Journal of clinical …, 2019 - Elsevier
Objective Low disease prevalence poses challenges for diagnostic accuracy studies because
of the large sample sizes that are required to obtain sufficient precision. The aim is to …