This report describes the first human study of a novel amyloid‐imaging positron emission
tomography (PET) tracer, termed Pittsburgh Compound‐B (PIB), in 16 patients with diagnosed …

Cardiac amyloidosis is a differential diagnosis in heart failure and is associated with high
mortality. There is currently no noninvasive imaging test available for specific diagnosis. N-[…

This report describes the synthesis of L-and D-[methyl-11C] methionine in pure enantiomeric
forms. The compounds were prepared routinely approximately 1,000 times with less than …

Over recent years, within the community of radiopharmaceutical sciences, there has been an
increased incidence of incorrect usage of established scientific terms and conventions, and …

Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as
positron emission tomography (PET) radioligands and are currently used to image various …

BACKGROUND: Aprepitant is a highly selective substance P (neurokinin 1 [NK 1 ] receptor)
antagonist that significantly improves the pharmacotherapy of acute and delayed highly …

Context Saturated fatty acid (SFA) vs polyunsaturated fatty acid (PUFA) may promote
nonalcoholic fatty liver disease by yet unclear mechanisms. Objective To investigate if overeating …

Purpose The aim of this study was to explore the cerebral distribution of the tau-specific PET
tracer [ 18 F]THK5317 (also known as (S)-[ 18 F]THK5117) retention in different stages of …

Clinical PET of apoptosis may have substantial value in advancing patient care. We report
here the first-in-humans study with 18 F-labeled 2-(5-fluoropentyl)-2-methyl malonic acid ( 18 …

Intracerebral microdialysis (MD) was applied in patients with subarachnoid hemorrhage.
The regional CBF, the CMRO 2 , and oxygen extraction ratio (OER) were measured with …