Introduction: Studies have shown that hydrogen sulfide (H 2 S), a gaseous neurotransmitter,
has neuroprotective effect. Here, we evaluated the neuroprotective activity of H 2 S in acute …

Purpose Studies argue in favor of hydrogen sulfide (H 2 S) as the next potent therapeutic
agent for neurodegenerative diseases. In present study, we investigated the effect of long term …

Mild to moderate dopaminergic (DA) neuronal death in substantia nigra pars compacta (SNc)
as the main pathological hallmark of Parkinson’s disease (PD) is usually silent and does …

Introduction: It is known that acute and chronic stress induce hormonal and neuronal changes
which affecting both pain threshold and nociceptive behaviours. Orexin plays an important …

Cerebellar Purkinje cells (PCs) are the sole output neurons of the cerebellar cortex. Mature
PCs discharge either tonically Na + spikes or bursts of Na + spikes ending to a Ca 2+ spike. …

Several lines of evidence show that homocysteine (Hcy) levels are increased in blood and
CSF of patients with Parkinson's disease. B vitamins are necessary for Hcy metabolism and …

Methods: The 6-OHDA was injected into striatum of rats by stereotaxic surgery. Treatment with
Glib and B vitamins was started before the surgery and continued up to 3 weeks after that. …

Orexin-A and orexin-B are two neuropeptides selectively synthesized in the lateral
hypothalamus (LH), a region involved in morphine induced analgesia and pain modulation. …

Studies have shown that hydrogen sulfide (H 2 S) exerts a neuroprotective effect and may
have a therapeutic value for treating neurodegenerative diseases including Parkinsonʼs …

Background Studies have shown that dexmedetomidine (DEX), a potent α 2 -adrenoceptors
agonist provides neuroprotection through suppression of inflammatory response. In present …