Bacteriophages are specific antagonists to bacterial hosts. These viral entities have attracted
growing interest as optimal vaccine delivery vehicles. Phages are well-matched for vaccine …

Human Toll-like receptors (TLRs) are a family of transmembrane receptors, which play a
key role in both innate and adaptive immune responses. Beside of recognizing specific …

Neonatal infection is associated with increased lifetime risk for neuropsychiatric disorders
including anxiety and depression, with evidence showing that dysregulation of the …

Over the recent decades, the use of antibody–drug conjugates (ADCs) has led to a paradigm
shift in cancer chemotherapy. Antibody–based treatment of various human tumors has …

Interleukin-21 (IL-21) is a member of the common γ-chain cytokines with broad pleiotropic
actions that affects different immune and nonimmune cells. IL-21 can affect differentiation, …

Cancer is one of the most important causes of death all over the world, which has not yet
been treated efficiently. Although several therapeutic approaches have been used, some side …

Fc-fusion proteins are composed of Fc region of IgG antibody (Hinge-CH2-CH3) and a
desired linked protein. Fc region of Fc-fusion proteins can bind to neonatal Fc receptor (FcRn) …

Phage display technology as a selection-based system is an attractive method for evolution
of new biological drugs. Unique ability of phage libraries for displaying proteins on …

Tumor microenvironment consists of malignant and non-malignant cells. The interaction of
these dynamic and different cells is responsible for tumor progression at different levels. The …

Immunosuppressive ability of mesenchymal stem cells (MSCs), their differentiation properties
to various specialized tissue types, ease of in vitro and in vivo expansion and specific …