Autosomal recessive primary microcephaly (MCPH) is a disorder of neurodevelopment
resulting in a small brain 1 , 2 . We identified WDR62 as the second most common cause of …

The monoclonal antibody RC2 was generated in mouse by conventional hybridoma
methodology. The antigen recognized by RC2 is robust, allowing aldehyde fixation appropriate to …

Three cell forms of astroglial lineage populate the prenatal and early postnatal murine cerebral
wall. In the present review we consider the ontogeny of these cell forms with respect to …

Severe myoclonic epilepsy of infancy (SMEI) or Dravet syndrome is a rare epilepsy syndrome.
In 30 to 70% of SMEI patients, truncating and missense mutations in the neuronal voltage‐…

Radial glial cells of the embryonic murine cerebral wall are selectively labeled by staining
with antibody RC1. In order to study the mitotic cycling of these cells, we combined RC1 …

Cells of astroglial lineage in the murine cerebrum undergo a succession of transformations
during prenatal and early postnatal development. The bipolar radial cell, the earliest …

Background Although continuity of care in paediatric palliative care (PPC) is considered to
be an essential element of quality of care, it’s implementation is challenging. In Belgium, five …

Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder with an incidence
of ∼1 in 4,000 live births. Neurofibromin, the gene product, is ubiquitously expressed at …

In Sub-Saharan Africa, intrarectal diazepam is the first-line anticonvulsant mostly used in
children. We aimed to assess this standard care against sublingual lorazepam, a medication …

Arachnoid cysts are benign congenital cavities arising in the subarachnoid space. Non-traumatic
subdural effusion of cerebrospinal fluid is a rare complication requiring surgical …