EANM procedure guidelines for PET brain imaging using [18F]FDG, version 2

…, T Vander Borght, J Booij, F Nobili, K Någren… - European journal of …, 2009 - Springer
These guidelines summarize the current views of the European Association of Nuclear
Medicine Neuroimaging Committee (ENC). The purpose of the guidelines is to assist nuclear …

Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain

V Kaasinen, H Vilkman, J Hietala, K Någren… - Neurobiology of …, 2000 - Elsevier
Loss of dopamine D2-like receptors in the striatum has been associated with both normal
human aging and impairment of cognitive and motor functions in the elderly. To investigate …

Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C] PIB positron emission tomography

…, VL Villemagne, G O'Keefe, K Någren… - Journal of Neurology …, 2008 - jnnp.bmj.com
Background: Neuropathological studies have reported varying amounts of amyloid
pathology in dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). [11C]PIB …

Frontal and temporal dopamine release during working memory and attention tasks in healthy humans: a positron emission tomography study using the high-affinity …

S Aalto, A Brück, M Laine, K Någren… - Journal of …, 2005 - Soc Neuroscience
Experimental studies on animals have shown that dopamine is a key neurotransmitter in the
regulation of working memory (WM) functions in the prefrontal cortex. In humans, blood flow …

EANM procedure guidelines for brain neurotransmission SPECT using 123I-labelled dopamine transporter ligands, version 2

…, T Vander Borght, ÖL Kapucu, K Någren… - European journal of …, 2010 - Springer
These guidelines summarize the current views of the European Association of Nuclear
Medicine Neuroimaging Committee (ENC). The aim of the guidelines is to assist nuclear …

[HTML][HTML] Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease

…, S DeSanti, N Kemppainen, K Någren… - European journal of …, 2008 - Springer
Objective The objective of the study is to compare the diagnostic value of regional sampling
of the cerebral metabolic rate of glucose metabolism (MRglc) using [18F]-fluoro-2-…

Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy

H Tuunanen, E Engblom, A Naum, K Någren… - Circulation, 2008 - Am Heart Assoc
Background— The anti-ischemic agent trimetazidine improves ejection fraction in heart failure
that is hypothetically linked to inhibitory effects on cardiac free fatty acid (FFA) oxidation. …

Sex Differences in the Striatal Dopamine D2 Receptor Binding Characteristics in Vivo

T Pohjalainen, JO Rinne, K Någren… - American Journal of …, 1998 - Am Psychiatric Assoc
OBJECTIVE: The authors investigated whether striatal dopamine D 2 receptor binding
characteristics in vivo are similar in men and women and whether there are sex-related …

Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease

…, S Aalto, M Karrasch, K Någren… - Annals of Neurology …, 2008 - Wiley Online Library
Objective The reduced risk for Alzheimer's disease (AD) in high‐educated individuals has
been proposed to reflect brain cognitive reserve, which would provide more efficient …

Myocardial efficiency during levosimendan infusion in congestive heart failure

…, H Iida, P Lehikoinen, K Någren… - Clinical …, 2000 - Wiley Online Library
Aims Levosimendan, a novel calcium‐dependent calcium sensitizer of the myocardial
contractile proteins, also enhances diastolic relaxation and induces peripheral vasodilation by …