[HTML][HTML] A review of HER4 (ErbB4) kinase, its impact on cancer, and its inhibitors

…, MA Emara, H Tarazi, RM Sbenati, MM Madkour… - Molecules, 2021 - mdpi.com
HER4 is a receptor tyrosine kinase that is required for the evolution of normal body systems
such as cardiovascular, nervous, and endocrine systems, especially the mammary glands. It …

Current status and future prospects of p38α/MAPK14 kinase and its inhibitors

MM Madkour, HS Anbar, MI El-Gamal - European journal of medicinal …, 2021 - Elsevier
P38α (which is also named MAPK14) plays a pivotal role in initiating different disease states
such as inflammatory disorders, neurodegenerative diseases, cardiovascular cases, and …

[HTML][HTML] Evaluation of substituted pyrazole-based kinase inhibitors in one decade (2011–2020): Current status and future prospects

MI El-Gamal, SO Zaraei, MM Madkour, HS Anbar - Molecules, 2022 - mdpi.com
Pyrazole has been recognized as a pharmacologically important privileged scaffold whose
derivatives produce almost all types of pharmacological activities and have attracted much …

Epigenetic modulations in cancer: predictive biomarkers and potential targets for overcoming the resistance to topoisomerase I inhibitors

MM Madkour, WS Ramadan, E Saleh… - Annals of …, 2023 - Taylor & Francis
Introduction Altered epigenetic map is frequently observed in cancer and recent investigations
have demonstrated a pertinent role of epigenetic modifications in the response to many …

Cerebral venous sinus thrombosis in Saudi Arabia

…, AP Abdu, AM Shami, AE Hassan, MA Madkour… - Neurosciences …, 2011 - nsj.org.sa
OBJECTIVE: To analyze the clinical patterns, etiologies, treatment, and outcome of cerebral
venous sinus thrombosis (CVST) in 2 major cities of Saudi Arabia, Jeddah and Al-Baha. …

Spectroscopic, biochemical and computational studies of bioactive DNA minor groove binders targeting 5′-WGWWCW-3′ motif

…, YA Msallam, HM Al-Jubeh, MM Madkour… - Bioorganic …, 2024 - Elsevier
Spectroscopic, biochemical, and computational modelling studies have been used to
assess the binding capability of a set of minor groove binding (MGB) ligands against the self-…

[HTML][HTML] Management of ST-segment elevation myocardial infarction in comparison to European society of cardiology guidelines in Alexandria University Hospitals …

A Kamal, A Zaki, A Abdelaaty, M Madkour - The Egyptian Heart Journal, 2023 - Springer
Background For patients with ST-elevation myocardial infarction (STEMI), early reperfusion
with primary percutaneous coronary intervention (PPCI) or thrombolytic treatment is essential …

Modulation of memory B cell phenotypes and toll-like receptor-7 in chronic hepatitis C virus infection during direct-acting antiviral interferon-free therapy: correlation …

H Moustafa, M Madkour, F Hamed… - Viral …, 2021 - liebertpub.com
Hepatitis C virus (HCV) infection is a major worldwide problem with the highest incidence
rates in Egypt. It affects B cells that serve as reservoirs for persistent HCV, resulting in …

Management of st-segment elevation myocardial infarction in comparison to european society of cardiology guidelines in alexandria university hospitals

M Madkour, A Zaki, A Abdelaty… - European Heart Journal …, 2022 - academic.oup.com
Aim The aim of this study was to determine the major contributors to reperfusion delay in ST-
elevation myocardial infarction (STEMI) patients in Alexandria University hospitals and the …

Trials For Preparation Of Combined Vaccine Of Equine Influenza, Equine Herpesvirus–1, Rabies Virus And Tetanus Toxoid

…, EM Ebied, NK Madkour… - Journal of Applied …, 2021 - javs.journals.ekb.eg
A combined vaccine of Equine influenza (EI), equine herpesvirus–1 (EHV-1), rabies virus
and tetanus toxoid adjuvanted with saponin and Alhydrogel was prepared. Quality control …