A diverse T cell repertoire is essential for a vigorous immune response to new infections, and
decreasing repertoire diversity has been implicated in the age-associated decline in CD8 T …

Background Sonchus asper (SA) is traditionally used for the treatment of various ailments
associated with liver, lungs and kidneys. This study was aimed to investigate the therapeutic …

There are well-characterized age-related changes in the peripheral repertoire of CD8 T cells
characterized by reductions in the ratio of naive: memory T cells and the development of …

Digital clubbing, recognized by Hippocrates in the fifth century BC, is the outward hallmark
of pulmonary hypertrophic osteoarthropathy, a clinical constellation that develops secondary …

Currently, nanotechnology is referred to be one of the attractive research sectors in several
countries because of its vast potential and commercial impact. Nanotechnology includes the …

Non-human primate models will expedite therapeutics and vaccines for coronavirus
disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …

Background Launaea procumbens (LP) has been used as a food supplement in Pakistan.
In this study methanolic crude extract (LPME) of the whole plant and its different fractions; n-…

The generation of effective type 1 T helper (Th1)‐cell responses is required for immunity
against intracellular bacteria. However, some intracellular bacteria require interleukin (IL)‐17 to …

The pro-inflammatory cytokine interleukin (IL)-17 (also known as IL-17) has been associated
with induction of tissue inflammation. Obese individuals exhibit many symptoms of chronic …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a global cause of death.
Granuloma-associated lymphoid tissue (GrALT) correlates with protection during TB, but the …