Improved neuroprotective effect of resveratrol nanoparticles as evinced by abrogation of rotenone-induced behavioral deficits and oxidative and mitochondrial …

S Palle, P Neerati - Naunyn-Schmiedeberg's Archives of Pharmacology, 2018 - Springer
The objective of the present study was to evaluate the protective effect of resveratrol nanoparticles
(NRSV) against rotenone-induced neurodegeneration in rats. NRSV were prepared …

Antiamnesic activity of Syzygium cumini against scopolamine induced spatial memory impairments in rats

…, VG Yerragunta, PR Veerareddy, S Palle - Brain and …, 2012 - Elsevier
We evaluated the Antiamnesic effects of methanolic extract of Syzygium cumini (MESC) on
spatial memory impairments induced by scopolamine (1mg/kg, ip), a muscarinic antagonist, …

[HTML][HTML] Quercetin nanoparticles attenuates scopolamine induced spatial memory deficits and pathological damages in rats

S Palle, P Neerati - Bulletin of Faculty of Pharmacy, Cairo University, 2017 - Elsevier
Quercetin is a well-known flavonoid, has low bioavailability. Quercetin nanoparticles (NQC)
enhance its bioavailability. NQC were not explored for their potential therapeutic activities in …

Gastroprotective and Antiulcer Effects of Celastrus paniculatus Seed Oil Against Several Gastric Ulcer Models in Rats

S Palle, A Kanakalatha, CN Kavitha - Journal of dietary …, 2018 - Taylor & Francis
Peptic ulcer is a recurrent chronic illness and has become almost a hallmark of the so-called
civilized life. In folk medicine, the Celastrus paniculatus plant has been used for the …

Fisetin improved rotenone-induced behavioral deficits, oxidative changes, and mitochondrial dysfunctions in rat model of Parkinson's disease

K Alikatte, S Palle, J Rajendra Kumar… - Journal of Dietary …, 2021 - Taylor & Francis
Oxidative stress plays an important role in the pathogenesis of Parkinson’s disease (PD),
particularly the inhibition of mitochondrial complex-I. This study aimed to evaluate the effect of …

Enhancement of oral bioavailability of rivastigmine with quercetin nanoparticles by inhibiting CYP3A4 and esterases

S Palle, P Neerati - Pharmacological Reports, 2017 - Elsevier
Background Quercetin is a well-known flavonoid, has pharmacokinetic interaction with ester
drugs due to its capability of esterase inhibition in the gut and liver. However, the interaction …

[PDF][PDF] Resveratrol nanoparticle pretreatment improved the oral bioavailability of bromocriptine: involvement of liver and intestinal CYP3A enzyme inhibition

P Neerati, S Palle - Journal of Natural Science, Biology and Medicine, 2019 - jnsbm.org
Background: Resveratrol (RSV) is a polyphenol belonging to phytoalexin family and has
been reported to show inhibitory effects on CYP3A4 enzymes. However, there has been no …

Antidopam inergic effects of leucine and genistein on shizophrenic rat models

P Suresh, AB Raju - Neurosciences Journal, 2013 - nsj.org.sa
OBJECTIVE: To evaluate the effect of leucine and genistein on the dopaminergic system in
a rat model of schizophrenia. METHODS: Behavioral effects of leucine and genistein on …

Quercetin nanoparticles alter pharmacokinetics of bromocriptine, reflecting its enhanced inhibitory action on liver and intestinal CYP 3A enzymes in rats

S Palle, P Neerati - Xenobiotica, 2018 - Taylor & Francis
Quercetin is a dietary flavonoid has extremely low water solubility and found to possess
CYP3A inhibitory activity. The purpose of the present study was to evaluate the effect of …

Gastroprotective and antiulcer effects of Celastrus paniculatus seed oil against several gastric ulcer models in rats.

SP Suresh Palle, A Kanakalatha, CN Kavitha - 2018 - cabidigitallibrary.org
Peptic ulcer is a recurrent chronic illness and has become almost a hallmark of the so-called
civilized life. In folk medicine, the Celastrus paniculatus plant has been used for the …